Evidence map›Paper›PMID 35186653›Full record

Article3 Biotech2022

Impact of dietary fructooligosaccharides (FOS) on murine gut microbiota and intestinal IgA secretion.

Aditi Jangid, Shinji Fukuda, Tamotsu Kato, Masahide Seki, Yutaka Suzuki, Todd D Taylor, Hiroshi Ohno, Tulika Prakash

Open access · greenAbstract read
In one paragraph

Article in 3 Biotech, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Macronutrients as Regulators of Intestinal Epithelial Permeability: Where Do We Stand?Comprehensive reviews in food science and food safety · 2025
    Review
  4. Yacon (Nutrients · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Aditi JangidSchool of Basic Sciences, Indian Institute of Technology (IIT) Mandi, Kamand, Mandi, Himachal Pradesh 175075 India.
Shinji FukudaInstitute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0052 Japan.
Tamotsu KatoLaboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045 Japan.
Masahide SekiDepartment of Computational Biology and Medical Sciences, The University of Tokyo, 5-1-5, Kashiwanoha, Kashiwa Chiba 277-8562 Japan.
Yutaka SuzukiDepartment of Computational Biology and Medical Sciences, The University of Tokyo, 5-1-5, Kashiwanoha, Kashiwa Chiba 277-8562 Japan.
Todd D TaylorLaboratory for Microbiome Sciences, RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama, Kanagawa 230-0045 Japan.
Hiroshi OhnoIntestinal Microbiota Project, Kanagawa Institute of Industrial Science and Technology, Kawasaki, Kanagawa 210-0821 Japan.
Tulika PrakashSchool of Basic Sciences, Indian Institute of Technology (IIT) Mandi, Kamand, Mandi, Himachal Pradesh 175075 India.ORCID 0000-0001-9270-8775
RIKEN Center for Integrative Medical Sciences · JPThe University of Tokyo · JPIndian Institute of Technology Mandi · INKanagawa Institute of Technology · JPYamagata University · JPYokohama City University Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fructooligosaccharides (FOS) are considered as prebiotics and are well known for their health-promoting properties, including antitumor, allergy-preventive, and infection-protective effects. They exert these effects by modulating the gut microbial composition and dynamics. In the present study, we performed a comparative whole metagenome shotgun sequencing analysis (WMGS) to elucidate the gut microbiota and secretary Immunoglobulin A (SIgA) dynamics as a result of 5% (w/w) FOS supplementation over a period of 7 days (fecal samples were collected every day). A number of taxa including SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13205-022-03116-3.

Indexed as

FOSImmunoglobulin AMetagenomicsNGS data analysisWhole metagenome shotgun sequencing

Identifiers

PMID35186653
PMCPMC8811108
OpenAlexW4210552350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.