ArticlePeerJ2022
Cross-sectional study of chromosomal aberrations and immunologic factors in Iraqi couples with recurrent pregnancy loss.
Article in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Anemia and cerebrovascular disease: pathophysiological insights and clinical implications.Annals of medicine and surgery (2012) · 2025Review
- Knowledge, Attitudes, and Practices of the General Population Regarding Peripheral Blood Chromosomal Testing in the Premarital or Preconception Context.Molecular genetics & genomic medicine · 2025Article
- The risks of autoimmune inflammatory outcomes in patients infected with SARS-CoV-2: a longitudinal, population-based cohort study.International journal of surgery (London, England) · 2025Article
- Kikuchi-Fujimoto disease: an unusual case report of lymphadenopathy with the absence of classic symptoms.Annals of medicine and surgery (2012) · 2025Article
- Improving the Diagnosis and Follow-Up of Chronic Myeloid Leukemia Using Conventional and Molecular Techniques.Journal of clinical laboratory analysis · 2025Article
- Identification of DNA damage repair-related genes in sepsis using bioinformatics and machine learning: An observational study.Medicine · 2025Observational
- Burden, causes, and treatment approaches of recurrent pregnancy loss: a scoping review.The Pan African medical journal · 2025Article
- Risk factors associated with pregnancy outcomes in patients with recurrent pregnancy loss after treatment.BMC pregnancy and childbirth · 2024Article
- Comparison of serum levels of interleukin 33 in combination with serum levels of C-reactive protein, Immunoglobulin G, Immunoglobulin A, and Immunoglobulin M in recurrent pregnancy loss: A case-control study.International journal of reproductive biomedicine · 2024Article
- Molecular cytogenetic analysis of multi-miscarriage products of conception in clinical cases from Al-Anbar Governorate, west of Iraq.Saudi journal of biological sciences · 2024Article
- The impact of circulating 25-hydroxyvitamin D and vitamin D receptor variation on leukemia-lymphoma outcome: Molecular and cytogenetic study.Saudi journal of biological sciences · 2024Article
- Article
- Chromosomal abnormalities in couples with recurrent pregnancy loss: a 16-year cross-sectional study of 4030 cases from Turkey.Annals of Saudi medicineArticle
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
backgroundParental chromosomal aberrations are important causes of recurrent pregnancy loss (RPL). Some immunological factors such as antiphospholipid antibodies and interleukin-6 (IL-6) also contribute to this complication. The aim of this study was to determine the frequency of chromosomal abnormalities and to evaluate some of the immunological factors in couples with RPL from different cities in Iraq.
methodsThis study was conducted on 25 couples (50 individuals) who had more than two first trimester abortions in the past and 25 healthy females as controls. Karyotyping was performed on peripheral blood of all participants. Anticardiolipin (IgG and IgM), antiphosopholipid (IgG and IgM), lupus anticoagulant, and IL-6 were assayed. Data were analyzed using appropriate statistical tests.
resultsChromosomal abnormalities were found in 28.0% (
conclusionIn this study, karyotyping revealed a high number of chromosomal abnormalities associated with the RPL in Iraqi couples. Since identification of genetic causes of miscarriage is important for genetic counseling and educating couples about the risk of future pregnancies, it is recommended that conventional karyotyping be investigated in patients with RPL.
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