Evidence map›Paper›PMID 35186220›Full record

ArticleJournal of healthcare engineering2022

On Improved 3D-CNN-Based Binary and Multiclass Classification of Alzheimer's Disease Using Neuroimaging Modalities and Data Augmentation Methods.

Ahsan Bin Tufail, Kalim Ullah, Rehan Ali Khan, Mustafa Shakir, Muhammad Abbas Khan, Inam Ullah, Yong-Kui Ma, Md Sadek Ali

RetractedAbstract readRetracted Publication
In one paragraph

Article in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Ahsan Bin TufailSchool of Electronics and Information Engineering, Harbin Institute of Technology, Harbin 150001, China.ORCID 0000-0002-1371-7647
Kalim UllahDepartment of Zoology, Kohat University of Science and Technology, Kohat 26000, Pakistan.
Rehan Ali KhanDepartment of Electrical Engineering, University of Science and Technology Bannu, Bannu 28100, Pakistan.
Mustafa ShakirDepartment of Electrical Engineering, Superior University, Lahore 54000, Pakistan.
Muhammad Abbas KhanDepartment of Electrical Engineering, Balochistan University of Information Technology,Engineering and Management Sciences, Quetta,Balochistan 87300, Pakistan.
Inam UllahCollege of Internet of Things (IoT) Engineering, Hohai University (HHU), Changzhou Campus 213022, China.ORCID 0000-0002-5879-569X
Yong-Kui MaSchool of Electronics and Information Engineering, Harbin Institute of Technology, Harbin 150001, China.ORCID 0000-0002-9535-5167
Md Sadek AliCommunication Research Laboratory, Department of Information and Communication Technology, Islamic University, Kushtia-7003, Bangladesh.ORCID 0000-0001-6253-5519

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is an irreversible illness of the brain impacting the functional and daily activities of elderly population worldwide. Neuroimaging sensory systems such as Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) measure the pathological changes in the brain associated with this disorder especially in its early stages. Deep learning (DL) architectures such as Convolutional Neural Networks (CNNs) are successfully used in recognition, classification, segmentation, detection, and other domains for data interpretation. Data augmentation schemes work alongside DL techniques and may impact the final task performance positively or negatively. In this work, we have studied and compared the impact of three data augmentation techniques on the final performances of CNN architectures in the 3D domain for the early diagnosis of AD. We have studied both binary and multiclass classification problems using MRI and PET neuroimaging modalities. We have found the performance of random zoomed in/out augmentation to be the best among all the augmentation methods. It is also observed that combining different augmentation methods may result in deteriorating performances on the classification tasks. Furthermore, we have seen that architecture engineering has less impact on the final classification performance in comparison to the data manipulation schemes. We have also observed that deeper architectures may not provide performance advantages in comparison to their shallower counterparts. We have further observed that these augmentation schemes do not alleviate the class imbalance issue.

Indexed as

Alzheimer DiseaseAgedBrainHumansMagnetic Resonance ImagingNeural Networks, ComputerNeuroimaging

Identifiers

PMID35186220
PMCPMC8856791

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.