Evidence map›Paper›PMID 35185909›Full record

ArticleFrontiers in immunology2022

Robust and Functional Immune Memory Up to 9 Months After SARS-CoV-2 Infection: A Southeast Asian Longitudinal Cohort.

Hoa Thi My Vo, Alvino Maestri, Heidi Auerswald, Sopheak Sorn, Sokchea Lay, Heng Seng, Sotheary Sann, Nisa Ya, Polidy Pean, Philippe Dussart and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  9. De novo design of anti-variant COVID-19 vaccine.Biology methods & protocols · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Hoa Thi My VoImmunology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Alvino MaestriImmunology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Heidi AuerswaldVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Sopheak SornEpidemiology and Public Health Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Sokchea LayImmunology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Heng SengDepartment of Communicable Disease Control, Ministry of Health (CDC-MoH), Phnom Penh, Cambodia.
Sotheary SannImmunology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Nisa YaImmunology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Polidy PeanImmunology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Philippe DussartVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Olivier SchwartzInstitut Pasteur, Université de Paris, CNRS UMR3569, Virus and Immunity Unit, Paris, France.
Sovann LyDepartment of Communicable Disease Control, Ministry of Health (CDC-MoH), Phnom Penh, Cambodia.
Timothée BruelInstitut Pasteur, Université de Paris, CNRS UMR3569, Virus and Immunity Unit, Paris, France.
Sowath LyEpidemiology and Public Health Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Veasna DuongVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Erik A KarlssonVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Tineke CantaertImmunology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Institut Pasteur du Cambodge · KHMinistry of Health · KHInstitut de Recherche Vaccinale · FRUniversité Paris Cité · FR

Funding

Howard Hughes Medical InstituteWellcome Trust
6 · The paper itself

Abstract

The duration of humoral and cellular immune memory following SARS-CoV-2 infection in populations in least developed countries remains understudied but is key to overcome the current SARS-CoV-2 pandemic. Sixty-four Cambodian individuals with laboratory-confirmed infection with asymptomatic or mild/moderate clinical presentation were evaluated for Spike (S)-binding and neutralizing antibodies and antibody effector functions during acute phase of infection and at 6-9 months follow-up. Antigen-specific B cells, CD4

Indexed as

Antibodies, NeutralizingAntibodies, ViralB-LymphocytesCambodiaCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCoronavirus Nucleocapsid ProteinsCOVID-19HumansImmunity, CellularImmunity, HumoralImmunologic MemoryPhosphoproteinsSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, NeutralizingAntibodies, ViralCoronavirus Nucleocapsid Proteinsnucleocapsid phosphoprotein, SARS-CoV-2PhosphoproteinsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2antibody effector functionB cell immunitylong term immune responseSARS-CoV-2T cell immunity

Identifiers

PMID35185909
PMCPMC8853741
OpenAlexW4210601064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.