Evidence map›Paper›PMID 35185855›Full record

ReviewFrontiers in microbiology2022

The Emerging Role of RNA Modifications in the Regulation of Antiviral Innate Immunity.

Jie Tong, Wuchao Zhang, Yuran Chen, Qiaoling Yuan, Ning-Ning Qin, Guosheng Qu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Review
  3. Augmented humoral responses to HIV Env trimers delivered as transmembrane immunogens by self-replicating RNA.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  4. Article
  5. Dynamic interplay between RNA NVeterinary research · 2025
    Article
  6. Article
  7. Review
  8. When animal viruses meet NVeterinary research · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Insight into the mechanisms of coronaviruses evading host innate immunity.Biochimica et biophysica acta. Molecular basis of disease · 2023
    Review
  14. Article
  15. Article
  16. Review
  17. Epitranscriptome: Review of Top 25 Most-Studied RNA Modifications.International journal of molecular sciences · 2022
    Review
  18. Methyltransferases ofBiomolecules · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jie TongCollege of Life Sciences, Hebei University, Baoding, China.
Wuchao ZhangCollege of Veterinary Medicine, Hebei Agricultural University, Baoding, China.
Yuran ChenCollege of Life Sciences, Hebei University, Baoding, China.
Qiaoling YuanCollege of Life Sciences, Hebei University, Baoding, China.
Ning-Ning QinCollege of Life Sciences, Hebei University, Baoding, China.
Guosheng QuCollege of Life Sciences, Hebei University, Baoding, China.
Hebei University · CNHebei Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posttranscriptional modifications have been implicated in regulation of nearly all biological aspects of cellular RNAs, from stability, translation, splicing, nuclear export to localization. Chemical modifications also have been revealed for virus derived RNAs several decades before, along with the potential of their regulatory roles in virus infection. Due to the dynamic changes of RNA modifications during virus infection, illustrating the mechanisms of RNA epigenetic regulations remains a challenge. Nevertheless, many studies have indicated that these RNA epigenetic marks may directly regulate virus infection through antiviral innate immune responses. The present review summarizes the impacts of important epigenetic marks on viral RNAs, including N6-methyladenosine (m

Indexed as

antiviral innate immunityIFN-IRIG-IRNA modificationviral infection

Identifiers

PMID35185855
PMCPMC8851159
OpenAlexW4210397799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.