Evidence map›Paper›PMID 35185776›Full record

ArticleFrontiers in neurology2022

Impaired Lower Limb Proprioception in Spinocerebellar Ataxia Type 3 and Its Affected Factors.

Xia-Hua Liu, Zhi-Yong Wang, Ying Li, Hao-Ling Xu, Arif Sikandar, Jun Ni, Shi-Rui Gan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xia-Hua LiuDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Zhi-Yong WangDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Ying LiThe Third Clinical Medical College, Fujian Medical University, Fuzhou, China.
Hao-Ling XuDepartment of Neurology, Institute of Neurology, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Arif SikandarDepartment of Neurology, Institute of Neurology, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Jun NiDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Shi-Rui GanDepartment of Neurology, Institute of Neurology, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Fujian Medical University · CNFirst Affiliated Hospital of Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpinocerebellar ataxia type 3 (SCA3) is one of the most common hereditary neurodegenerative diseases. Postural control dysfunction is the main symptom of SCA3, and the proprioceptive system is a critical sensory component of postural control. Accordingly, proprioception quantification assessment is necessary in monitoring the progression of SCA3.

objectiveWe aimed to quantitatively assess lower limb proprioception and investigate the relationship between proprioception and clinical characteristics in patients with SCA3.

methodsA total of 80 patients with SCA3 and 62 health controls were recruited, and their lower limb proprioception was measured using the Pro-kin system. Clinical characteristics of the SCA3 patients were collected. Multivariable linear regression was used to investigate potential affected factors for lower limb proprioception.

resultsWe found that the patients with SCA3 experience poorer lower limb proprioception characterized by significant impairment in the average trace error (ATE) and time to carry out the test time execution (TTE) compared to controls (

conclusionsLower limb proprioception in patients with SCA3 is significantly impaired when compared to healthy controls. Increasing AAO and disease duration are related to impaired lower limb proprioception.

Indexed as

disease progressionlower limb proprioceptionpostural controlPro-kin systemspinocerebellar ataxia type 3

Identifiers

PMID35185776
PMCPMC8847775
OpenAlexW4210526704

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.