ArticleFrontiers in neurology2021
Association Between Lipid Accumulation Product and Cognitive Function in Hypertensive Patients With Normal Weight: Insight From the China H-type Hypertension Registry Study.
Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Novel anthropometric indices and cognitive function among iranian older adults: Bushehr Elderly Health (BEH) program.PloS one · 2026Article
- Association between lipid accumulation product and cognitive impairment: a community-based 4-year prospective cohort study.Aging clinical and experimental research · 2025Article
- Association between lipid accumulation product and non-alcoholic fatty liver disease with normal weight: a population-based study.Frontiers in medicine · 2025Article
- Physical activity, sleep disorders, and type of work in the prevention of cognitive function decline in patients with hypertension.BMC public health · 2023Article
- The effect of lipid metabolism on age-associated cognitive decline: Lessons learned from model organisms and human.IBRO neuroscience reports · 2023Article
- The Triglyceride-Glucose Index Is Associated with Longitudinal Cognitive Decline in a Middle-Aged to Elderly Population: A Cohort Study.Journal of clinical medicine · 2022Article
- Threshold effect of plasma total homocysteine levels on cognitive function among hypertensive patients in China: A cross-sectional study.Frontiers in neurology · 2022Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertension is a major cardiovascular risk factor for cognitive impairment. Lipid accumulation product (LAP), an index that represents fat overaccumulation in the body, has been shown to be associated with cardiovascular disease. Nevertheless, the relationship between LAP and cognitive function in hypertensive patients with normal weight has been infrequently studied.
objectiveThis study aimed to assess the relationship between LAP and cognitive function in hypertensive patients with normal weight.
methodsThis study included 5,542 Chinese hypertensive patients with normal weight. Cognitive function was evaluated using the Mini-Mental State Examination (MMSE). The relationship between LAP and MMSE scores was evaluated using multiple linear regression.
resultsThe mean age of the participants was 64.8 ± 9.3 years, and 2,700 were men (48.7%). The mean MMSE score was 24.5 ± 5.1 in men and 19.2 ± 6.5 in women. The mean LAP was 26.2 ± 25.5 in men and 42.5 ± 34 in women. Log
conclusionLAP showed an independent positive association with MMSE in Chinese hypertensive patients with normal weight.
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Registered trials
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