ArticleFrontiers in physiology2021
Transcriptome Responses to Defined Insecticide Selection Pressures in the German Cockroach (
Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Exploring and Mitigating Insecticide Resistance in Urban Pests with New Synergists and Insecticides.Insects · 2026Review
- Midgut microbiota profiling of Blattella germanica (Blattodea: Ectobiidae).Journal of insect science (Online) · 2026Article
- Multi-omics of cockroaches infected with Salmonella Typhimurium identifies molecular signatures of vector colonization.BMC genomics · 2025Article
- Article
- Behavioral and Transcriptomic Analyses in the Indoxacarb Response of a Non-Target Damselfly Species.Insects · 2024Article
- Effects of copper and zinc oxide nanoparticles on German cockroach development, indoxacarb resistance, and bacterial load.Pest management science · 2023Article
- Impacts of Bioassay Type on Insecticide Resistance Assessment in the German Cockroach (Blattodea: Ectobiidae).Journal of medical entomology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cockroaches are important global urban pests from aesthetic and health perspectives. Insecticides represent the most cost-effective way to control cockroaches and limit their impacts on human health. However, cockroaches readily develop insecticide resistance, which can quickly limit efficacy of even the newest and most effective insecticide products. The goal of this research was to understand whole-body physiological responses in German cockroaches, at the metatranscriptome level, to defined insecticide selection pressures. We used the insecticide indoxacarb as the selecting insecticide, which is an important bait active ingredient for cockroach control. Six generations of selection with indoxacarb bait produced a strain with substantial (>20×) resistance relative to inbred control lines originating from the same parental stock. Metatranscriptome sequencing revealed 1,123 significantly differentially expressed (DE) genes in ≥two of three statistical models (81 upregulated and 1,042 downregulated; FDR
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