ArticleFrontiers in pharmacology2022
The Effects of Different Doses of Alfentanil and Dexmedetomidine on Prevention of Emergence Agitation in Pediatric Tonsillectomy and Adenoidectomy Surgery.
Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06306040 (Effect of Intravenous Nalbuphine Versus Magnesium Sulfate on Emergence Agitation in Pediatric Patients Scheduled for Hypospadias Repair), which is not on this map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Intravenous Nalbuphine Versus Magnesium Sulfate on Emergence Agitation in Pediatric Patients Scheduled for Hypospadias Repair
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Efficacy of dexmedetomidine in preventing emergence agitation in children undergoing tonsillectomy and/or adenoidectomy: a meta-analysis and systematic review.BMC anesthesiology · 2025Pooled it
- Evaluating dexmedetomidine in mitigating emergence agitation and perioperative complications in pediatric tonsillectomy and/or adenoidectomy: a systematic review and meta-analysis.Frontiers in pharmacology · 2025Pooled it
- The effects of alfentanil on emergence agitation in children under general anesthesia: a meta-analysis of randomized controlled trials.Frontiers in pediatrics · 2025Pooled it
- Optimizing adjuvant strategies for sevoflurane-related emergence delirium: a Bayesian network meta-analysis in pediatric surgery.Frontiers in pharmacology · 2025Pooled it
- Trial
- The Effects of Different Doses of Nalbuphine and Esketamine on Prevention of Emergence Agitation in Preschool Children Undergoing Tonsillectomy and Adenoidectomy: A Randomized Clinical Trial.Drug design, development and therapy · 2026Trial
- Effects of Ciprofol Combined with Varying Doses of Alfentanil on Anesthetic Efficacy and Safety in Pediatric Bronchoscopy: A Randomized Controlled Trial.Drug design, development and therapy · 2026Trial
- Comparing different administration methods of subanaesthetic propofol to mitigate emergence agitation in preschool children undergoing day surgery: a double-blind, randomised controlled study.BMJ paediatrics open · 2025Trial
- Compare the Effects of 0 mg/kg, 0.1 mg/kg, 0.3 mg/kg and 0.5 mg/kg Esketamine on Emergence Agitation After Tonsillectomy and Adenoidectomy in Children: A Randomized Control Trial.Drug design, development and therapy · 2025Trial
- Preoperative interventions for reducing anxiety in school-age children undergoing surgery: a network meta-analysis.The Cochrane database of systematic reviews · 2026Article
- Predictive value of surgical pleth index for early postoperative pain in children undergoing general anesthesia: a prospective observational study.BMC anesthesiology · 2025Observational
- The efficacy and safety of remimazolam for the management of emergence agitation: a randomized, double-blind, placebo-controlled study.Frontiers in medicine · 2025Article
- Hydromorphone reduced the incidence of emergence agitation after adenotonsillectomy in children with obstructive sleep apnea: A randomized, double-blind study.Open medicine (Warsaw, Poland) · 2025Article
- Perioperative complications of middle cerebral artery occlusion in rats alleviated by human umbilical cord mesenchymal stem cells.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- Electroencephalographic insights into the pathophysiological mechanisms of emergence delirium in children and corresponding clinical treatment strategies.Frontiers in pharmacology · 2024Review
- Effects of glycopyrrolate and atropine for oral secretions and perioperative hemodynamics in children undergoing tonsillectomy and adenoidectomy: a prospective, single-center, randomized, double-blind, controlled trial.Frontiers in pharmacology · 2024Article
- Tracheal extubation under Narcotrend EEG monitoring at different depths of anesthesia after tonsillectomy in children: a prospective randomized controlled study.Frontiers in pediatrics · 2024Article
- Prevalence and risk factors of emergence agitation among pediatric patients undergo ophthalmic and ENT Surgery: a cross-sectional study.BMC pediatrics · 2023Article
- A systematic review and meta-analysis on the efficacy and safety of dexmedetomidine combined with sevoflurane anesthesia on emergence agitation in children.Translational pediatrics · 2022Article
- Magnetic Resonance Imaging Characteristic Evaluation of Dexmedetomidine on Neurocognitive Dysfunction in Elderly Patients with Colorectal Tumors after Laparoscopic Operation.Computational and mathematical methods in medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.