Evidence map›Paper›PMID 35185494›Full record

ArticleFrontiers in human neuroscience2021

Regional Haemodynamic and Metabolic Coupling in Infants.

Maheen F Siddiqui, Paola Pinti, Sarah Lloyd-Fox, Emily J H Jones, Sabrina Brigadoi, Liam Collins-Jones, Ilias Tachtsidis, Mark H Johnson, Clare E Elwell

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Maheen F SiddiquiCentre for Brain and Cognitive Development, Birkbeck College, University of London, London, United Kingdom.
Paola PintiCentre for Brain and Cognitive Development, Birkbeck College, University of London, London, United Kingdom.
Sarah Lloyd-FoxDepartment of Psychology, University of Cambridge, Cambridge, United Kingdom.
Emily J H JonesCentre for Brain and Cognitive Development, Birkbeck College, University of London, London, United Kingdom.
Sabrina BrigadoiDepartment of Development and Social Psychology, University of Padua, Padua, Italy.
Liam Collins-JonesDepartment of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.
Ilias TachtsidisDepartment of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.
Mark H JohnsonDepartment of Psychology, University of Cambridge, Cambridge, United Kingdom.
Clare E ElwellDepartment of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.
Birkbeck, University of London · GBUniversity College London · GBUniversity of Cambridge · GBUniversity of Padua · IT

Funding

Medical Research Council MR/K021389/1Medical Research Council MR/S018425/1Medical Research Council MR/T003057/1
6 · The paper itself

Abstract

Metabolic pathways underlying brain function remain largely unexplored during neurodevelopment, predominantly due to the lack of feasible techniques for use with awake infants. Broadband near-infrared spectroscopy (bNIRS) provides the opportunity to explore the relationship between cerebral energy metabolism and blood oxygenation/haemodynamics through the measurement of changes in the oxidation state of mitochondrial respiratory chain enzyme cytochrome-c-oxidase (ΔoxCCO) alongside haemodynamic changes. We used a bNIRS system to measure ΔoxCCO and haemodynamics during functional activation in a group of 42 typically developing infants aged between 4 and 7 months. bNIRS measurements were made over the right hemisphere over temporal, parietal and central cortical regions, in response to social and non-social visual and auditory stimuli. Both ΔoxCCO and Δ[HbO

Indexed as

brain metabolic imagingbrain specializationfNIRS (functional near infrared spectroscopy)metabolismmitochondrianeurodevelopmentneurovascular couplingsocial brain

Identifiers

PMID35185494
PMCPMC8854371
OpenAlexW4210788176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.