Evidence map›Paper›PMID 35185449›Full record

ArticleFrontiers in neuroscience2021

The Contribution of Anterior Segment Abnormalities to Changes in Intraocular Pressure in the DBA/2J Mouse Model of Glaucoma: DBA/2J-

Landon J Rohowetz, Marc E Mardelli, R Scott Duncan, Sean M Riordan, Peter Koulen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Genetic Diagnosis and Discovery Enabled by Large Language Models.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Genetic Discovery Enabled by A Large Language Model.bioRxiv : the preprint server for biology · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Landon J RohowetzDepartment of Ophthalmology, Vision Research Center, School of Medicine, University of Missouri - Kansas City, Kansas City, MO, United States.
Marc E MardelliDepartment of Ophthalmology, Vision Research Center, School of Medicine, University of Missouri - Kansas City, Kansas City, MO, United States.
R Scott DuncanDepartment of Ophthalmology, Vision Research Center, School of Medicine, University of Missouri - Kansas City, Kansas City, MO, United States.
Sean M RiordanDepartment of Ophthalmology, Vision Research Center, School of Medicine, University of Missouri - Kansas City, Kansas City, MO, United States.
Peter KoulenDepartment of Ophthalmology, Vision Research Center, School of Medicine, University of Missouri - Kansas City, Kansas City, MO, United States.
City Vision University · USUniversity of Missouri–Kansas City · US

Funding

Novel mechanism controlling calcium signaling to treat and prevent neurodegeneration in early stage glaucomaR01EY031248 · NEI · UNIVERSITY OF MISSOURI KANSAS CITY · PI KOULEN, PETER · 2020 to 2022
$1.7M
Novel mechanism of action as therapeutic strategy for optic neuritisR01EY022774 · NEI · UNIVERSITY OF MISSOURI KANSAS CITY · PI KOULEN, PETER · 2012 to 2014
$1.2M
Confocal Laser Scanning MicroscopeS10RR027093 · NCRR · UNIVERSITY OF MISSOURI KANSAS CITY · PI KOULEN, PETER · 2010 to 2010
$497k
NCRR NIH HHS S10 RR027093NEI NIH HHS R01 EY022774NEI NIH HHS R01 EY031248
6 · The paper itself

Abstract

The contributions of anterior segment abnormalities to the development of ocular hypertension was determined in the DBA/2J mouse model of glaucoma. Intraocular pressure (IOP) was measured non-invasively. Iris pigment dispersion (IPD) and corneal calcification were measured weekly starting at 20 weeks of age in DBA/2J and DBA/2J-

Indexed as

anterior chambercorneacorneal calcificationglaucomaintraocular pressureiris pigment dispersioniris stromal atrophyretina

Identifiers

PMID35185449
PMCPMC8850401
OpenAlexW4210472293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.