Evidence map›Paper›PMID 35185052›Full record

ArticleInternal medicine (Tokyo, Japan)2022

Chronic Enteropathy Associated with Solute Carrier Organic Anion Transporter Family, Member 2A1 (SLCO2A1) with Positive Immunohistochemistry for SLCO2A1 Protein.

Chizuru Ariake, Naoki Hosoe, Hinako Sakurai, Anna Tojo, Yukie Hayashi, Kenji Jl Limpias Kamiya, Tomohisa Sujino, Kaoru Takabayashi, Kenjiro Kosaki, Satowa Seki and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Chronic Enteropathy Associated withInflammatory intestinal diseases
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Chizuru AriakeCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Japan.
Naoki HosoeCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Japan.
Hinako SakuraiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Anna TojoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Yukie HayashiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Kenji Jl Limpias KamiyaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Tomohisa SujinoCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Japan.
Kaoru TakabayashiCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Japan.
Kenjiro KosakiCenter for Medical Genetics, Keio University School of Medicine, Japan.
Satowa SekiDepartment of Gastroenterology and Hepatology, Kyorin University School of Medicine, Japan.
Tadakazu HisamatsuDepartment of Gastroenterology and Hepatology, Kyorin University School of Medicine, Japan.
Haruhiko OgataCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Japan.
Takanori KanaiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Japan.
Keio University · JPKyorin University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic enteropathy associated with solute carrier organic anion transporter family, member 2A1 (SLCO2A1) (CEAS) is a rare autosomal recessive hereditary disease characterized by chronic persistent anemia and hypoproteinemia. Its diagnosis typically requires a genetic analysis. The efficacy of immunohistochemical staining with SLCO2A1 polyclonal antibody as a pre-diagnostic tool for CEAS has been previously reported. We herein report a patient with CEAS in whom immunohistochemical staining confirmed SLCO2A1 protein expression. The immunopositive results may have been due to nonsense-mediated RNA decay. As immunohistochemical staining of SLCO2A1 protein may show immunopositive results, a genetic analysis should also be performed when CEAS is strongly clinically suspected.

Indexed as

Inflammatory Bowel DiseasesOrganic Anion TransportersGenetic TestingHumansImmunohistochemistryOrganic Anion TransportersSLCO2A1 protein, humanballoon-assisted enteroscopychronic enteropathy associated with SLCO2A1 genesmall intestinevideo capsule endoscopy

Identifiers

PMID35185052
PMCPMC9492477
OpenAlexW4213010955

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.