Evidence map›Paper›PMID 35185010›Full record

ArticleBritish journal of sports medicine2022

Cost-effectiveness of full endoscopic versus open discectomy for sciatica.

Pravesh Shankar Gadjradj, Hana M Broulikova, Johanna M van Dongen, Sidney M Rubinstein, Paul R Depauw, Carmen Vleggeert, Ankie Seiger, Wilco C Peul, Job L van Susante, Maurits W van Tulder and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in British journal of sports medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02602093 (), which is not on this map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02602093 naunknown statusnot on this map

(Cost) Effectiveness of Percutaneous Transforaminal Endoscopic Discectomy vs. Open Microdiscectomy for Patients With Symptomatic Lumbar Disc Herniation

TypeinterventionalSponsorAmsterdam UMC, location VUmcRan2016 to 2024Enrolled682ConditionsLumbar Disk HerniationArmsTransforaminal Endoscopic Discectomy, Open Microdiscectomy
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Lumbar Disc Herniation: What's New in Surgical Treatment.Revista brasileira de ortopedia · 2026
    Article
  7. Endoscopic spine surgery.Bulletin of the Hospital for Joint Disease (2013) · 2026
    Review
  8. Article
  9. Article
  10. Feasibility and accuracy of AI-assisted 3D MRI/CT fusion imaging for preoperative simulation of full-endoscopic transforaminal discectomy.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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  12. Article
  13. Article
  14. Review
  15. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pravesh Shankar GadjradjDepartment of Neurological Surgery, Weill Cornell Brain and Spine Center, New York-Presbyterian/Weil Cornell Medicine New York, New York, USA.ORCID http://orcid.org/0000-0001-9672-4238
Hana M BroulikovaDepartment of Health Sciences, Faculty of Science, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Johanna M van DongenDepartment of Health Sciences, Faculty of Science, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Sidney M RubinsteinFaculty of Behavioural and Movement Sciences, Amsterdam Movement Sciences research institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Paul R DepauwDepartment of Neurosurgery, Elisabeth-TweeSteden Ziekenhuis, Tilburg, The Netherlands.
Carmen VleggeertDepartment of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands.
Ankie SeigerFaculty of Behavioural and Movement Sciences, Amsterdam Movement Sciences research institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Wilco C PeulDepartment of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands.
Job L van SusanteDepartment of Orthopedic Surgery, Rijnstate, Arnhem, The Netherlands.
Maurits W van TulderFaculty of Behavioural and Movement Sciences, Amsterdam Movement Sciences research institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Biswadjiet S HarhangiDepartment of Neurosurgery, Erasmus MC, Rotterdam, The Netherlands b.s.harhangi@erasmusmc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the costs and cost-effectiveness of percutaneous transforaminal endoscopic discectomy (PTED) compared with open microdiscectomy among patients with sciatica.

methodsThis economic evaluation was conducted alongside a 12-month multicentre randomised controlled trial with a non-inferiority design, in which patients were randomised to PTED or open microdiscectomy. Patients were aged from 18 to 70 years and had at least 6 weeks of radiating leg pain caused by lumbar disc herniation. Effect measures included leg pain and quality-adjusted life years (QALYs), as derived using the EQ-5D-5L. Costs were measured from a societal perspective. Missing data were multiply imputed, bootstrapping was used to estimate statistical uncertainty, and various sensitivity analyses were conducted to determine the robustness.

resultsOf the 613 patients enrolled, 304 were randomised to PTED and 309 to open microdiscectomy. Statistically significant differences in leg pain and QALYs were found in favour of PTED at 12 months follow-up (leg pain: 6.9; 95% CI 1.3 to 12.6; QALYs: 0.040; 95% CI 0.007 to 0.074). Surgery costs were higher for PTED than for open microdiscectomy (ie, €4500/patient vs €4095/patient). All other disaggregate costs as well as total societal costs were lower for PTED than for open microdiscectomy. Cost-effectiveness acceptability curves indicated that the probability of PTED being less costly and more effective (ie, dominant) compared with open microdiscectomy was 99.4% for leg pain and 99.2% for QALYs.

conclusionsOur results suggest that PTED is more cost-effective from the societal perspective compared with open microdiscectomy for patients with sciatica. TRIAL REGISTRATION NUMBER: NCT02602093.

Indexed as

arthroscopyrandomized controlled trialspine

Identifiers

PMID35185010
PMCPMC9484367

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.