Evidence map›Paper›PMID 35184772›Full record

ArticleEpidemiology and infection2022

Outbreak of COVID-19 among children and young adults in a cancer centre daycare unit.

Ki Wook Yun, Ye Kyung Kim, Eun Sun Song, Hong Yul An, Kyung Taek Hong, Jung Yoon Choi, Hyoung Jin Kang, Seung Min Chung, In Kyung Park, Hyo Yeon Lee and 2 more

Abstract read
In one paragraph

Article in Epidemiology and infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. COVID-19 in immunocompromised children and adolescents.Clinical and experimental pediatrics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ki Wook YunDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-0798-6779
Ye Kyung KimDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Eun Sun SongDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Hong Yul AnDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Kyung Taek HongDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jung Yoon ChoiDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Hyoung Jin KangDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea.
Seung Min ChungInfection Prevention and Control Center, Seoul National University Hospital, Seoul, Republic of Korea.
In Kyung ParkInfection Prevention and Control Center, Seoul National University Hospital, Seoul, Republic of Korea.
Hyo Yeon LeeInfection Prevention and Control Center, Seoul National University Hospital, Seoul, Republic of Korea.
Nam Joong KimInfection Prevention and Control Center, Seoul National University Hospital, Seoul, Republic of Korea.
Eun Hwa ChoiDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nosocomial transmission of COVID-19 among immunocompromised hosts can have a serious impact on COVID-19 severity, underlying disease progression and SARS-CoV-2 transmission to other patients and healthcare workers within hospitals. We experienced a nosocomial outbreak of COVID-19 in the setting of a daycare unit for paediatric and young adult cancer patients. Between 9 and 18 November 2020, 473 individuals (181 patients, 247 caregivers/siblings and 45 staff members) were exposed to the index case, who was a nursing staff. Among them, three patients and four caregivers were infected. Two 5-year-old cancer patients with COVID-19 were not severely ill, but a 25-year-old cancer patient showed prolonged shedding of SARS-CoV-2 RNA for at least 12 weeks, which probably infected his mother at home approximately 7-8 weeks after the initial diagnosis. Except for this case, no secondary transmission was observed from the confirmed cases in either the hospital or the community. To conclude, in the day care setting of immunocompromised children and young adults, the rate of in-hospital transmission of SARS-CoV-2 was 1.6% when applying the stringent policy of infection prevention and control, including universal mask application and rapid and extensive contact investigation. Severely immunocompromised children/young adults with COVID-19 would have to be carefully managed after the mandatory isolation period while keeping the possibility of prolonged shedding of live virus in mind.

Indexed as

Cancer Care FacilitiesDay Care, MedicalInfectious Disease Transmission, Professional-to-PatientAdolescentAdultAgedCaregiversChildChild, PreschoolCOVID-19Cross InfectionDisease OutbreaksFemaleHumansImmunocompromised HostInfantchildrenCOVID-19immunocompromisednosocomialSARS-CoV-2

Identifiers

PMID35184772
PMCPMC8886074

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.