Evidence map›Paper›PMID 35184610›Full record

ArticleThe Journal of international medical research2022

Basophilic stippling in red blood cells in the bone marrow: indication for lead poisoning diagnosis.

Nagamasa Kano, Sayato Fukui, Seiko Kushiro, Akihiro Inui, Mizue Saita, Yoshimasa Kura, Umihiko Sawada, Toshio Naito

Open access · goldAbstract readCase Reports
In one paragraph

Article in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
    Article
  2. Burton line and basophilic stippling in lead poisoning.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nagamasa KanoDepartment of General Medicine, Juntendo University Faculty of Medicine, Japan.
Sayato FukuiDepartment of General Medicine, Juntendo University Faculty of Medicine, Japan.ORCID https://orcid.org/0000-0002-1658-2223
Seiko KushiroDepartment of General Medicine, Juntendo University Faculty of Medicine, Japan.
Akihiro InuiDepartment of General Medicine, Juntendo University Faculty of Medicine, Japan.
Mizue SaitaDepartment of General Medicine, Juntendo University Faculty of Medicine, Japan.
Yoshimasa KuraDepartment of Hematology, 36850Kasukabe Medical Center, Kasukabe Medical Center, Japan.
Umihiko SawadaDepartment of Hematology, 36850Kasukabe Medical Center, Kasukabe Medical Center, Japan.
Toshio NaitoDepartment of General Medicine, Juntendo University Faculty of Medicine, Japan.
Juntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 40-year-old man presented at our hospital with anaemia that had been undiagnosed for 2 years. Blood tests, endoscopy, and contrast-enhanced computed tomography were performed, but a definitive diagnosis could not be made. A subsequent bone marrow biopsy revealed basophilic stippling in transformed red blood cells, which led to a differential diagnosis of lead poisoning. Additional tests revealed elevated levels of lead in the blood. Basophilic stippling is generally found on a peripheral blood smear in lead poisoning patients; however, in this case, basophilic stippling was found only on the bone marrow smear and not in the blood smear. Even if basophilic stippling is not found in the peripheral blood, lead poisoning cannot be excluded.

Indexed as

AnemiaLead PoisoningAdultBone MarrowErythrocyte CountErythrocytesHumansMaleanaemiabasophilic stipplingblood smearbone marrow biopsyLead poisoningtransformed red blood cell

Identifiers

PMID35184610
PMCPMC8864261
OpenAlexW4213038865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.