Evidence map›Paper›PMID 35184407›Full record

ArticleClinical and translational medicine2022

Hyperactivation of platelet-derived growth factor signalling contributes to arrhythmogenesis in Brugada syndrome.

Hongkun Wang, Lizhen Xu, Shuai Han, Xiaochen Wang, Hao Wang, Jingjun Zhou, Jiaxi Shen, Zongkuai Yang, Luyang Yu, Zhouqing Huang and 4 more

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Hongkun WangKey Laboratory of combined Multi-organ Transplantation, Ministry of Public Health, the First Affiliated Hospital, Zhejiang University, Hangzhou, China.
Lizhen XuDepartment of Biophysics, and Kidney Disease Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Shuai HanDepartment of Obstetrics, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Xiaochen WangKey Laboratory of combined Multi-organ Transplantation, Ministry of Public Health, the First Affiliated Hospital, Zhejiang University, Hangzhou, China.
Hao WangDepartment of Prenatal Diagnosis (Screening) Center, Hangzhou Women's Hospital (Hangzhou Maternity and Child Health Care Hospital), Hangzhou, China.
Jingjun ZhouKey Laboratory of combined Multi-organ Transplantation, Ministry of Public Health, the First Affiliated Hospital, Zhejiang University, Hangzhou, China.
Jiaxi ShenKey Laboratory of combined Multi-organ Transplantation, Ministry of Public Health, the First Affiliated Hospital, Zhejiang University, Hangzhou, China.
Zongkuai YangKey Laboratory of combined Multi-organ Transplantation, Ministry of Public Health, the First Affiliated Hospital, Zhejiang University, Hangzhou, China.
Luyang YuCollege of Life Sciences, Zhejiang University, Hangzhou, China.
Zhouqing HuangDepartment of Cardiology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Tingyu GongKey Laboratory of combined Multi-organ Transplantation, Ministry of Public Health, the First Affiliated Hospital, Zhejiang University, Hangzhou, China.
Ming QiDepartment of Cell Biology and Medical Genetics, Zhejiang University School of Medicine, Hangzhou, China.
Fan YangDepartment of Biophysics, and Kidney Disease Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Ping LiangKey Laboratory of combined Multi-organ Transplantation, Ministry of Public Health, the First Affiliated Hospital, Zhejiang University, Hangzhou, China.ORCID 0000-0001-6806-3735
Ministry of Public Health · MGFirst Affiliated Hospital Zhejiang University · CNHangzhou Women’s Hospital · CNZhejiang University · CNWenzhou Medical University · CNZhejiang Provincial People's Hospital · CN

Funding

National Key R&D Program of China 2017YFA0103700National Natural Science Foundation of China 31571528National Natural Science Foundation of China 81870175National Natural Science Foundation of China 81922006Natural Science Foundation of Zhejiang Province LD21H020001Natural Science Foundation of Zhejiang Province LR15H020001
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Arrhythmias, CardiacBrugada SyndromeHumansPlatelet-Derived Growth FactorTRPM Cation ChannelsPlatelet-Derived Growth FactorTRPM4 protein, humanTRPM Cation Channels

Identifiers

PMID35184407
PMCPMC8858633
OpenAlexW4212926681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.