Evidence map›Paper›PMID 35184391›Full record

ReviewChemical biology & drug design2022

SARS-CoV-2 and its variants of concern including Omicron: A never ending pandemic.

Ranjan K Mohapatra, Satwik Kuppili, Tarun Kumar Suvvari, Venkataramana Kandi, Ajit Behera, Sarika Verma, Kudrat-E-Zahan, Susanta K Biswal, Taghreed H Al-Noor, Marei M El-Ajaily and 2 more

Abstract readReview
In one paragraph

Review in Chemical biology & drug design, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Immunization against Medically Important Human Coronaviruses of Public Health Concern.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Review
  8. Article
  9. Bacterial Artificial Chromosome Reverse Genetics Approaches for SARS-CoV-2.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ranjan K MohapatraDepartment of Chemistry, Government College of Engineering, Keonjhar, Odisha, India.ORCID 0000-0001-7623-3343
Satwik KuppiliNTR University of Health Sciences, Andhra Pradesh, India.
Tarun Kumar SuvvariNTR University of Health Sciences, Andhra Pradesh, India.
Venkataramana KandiDepartment of Microbiology, Prathima Institute of Medical Sciences, Karimnagar, Telangana, India.
Ajit BeheraDepartment of Metallurgical & Materials Engineering, National Institute of Technology, Rourkela, India.
Sarika VermaCouncil of Scientific and Industrial Research-Advanced Materials and Processes Research Institute, Bhopal, MP, India.
Kudrat-E-ZahanDepartment of Chemistry, Rajshahi University, Rajshahi, Bangladesh.
Susanta K BiswalDepartment of Chemistry, School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Taghreed H Al-NoorChemistry Department, Ibn-Al-Haithem College of Education for Pure Science, Baghdad University, Baghdad, Iraq.
Marei M El-AjailyChemistry Department, Faculty of Science, Benghazi University, Benghazi, Libya.
Ashish K SarangiDepartment of Chemistry, School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.ORCID 0000-0002-5602-4736
Kuldeep DhamaDivision of Pathology, ICAR-Indian Veterinary Research Institute, Uttar Pradesh, Bareilly, India.ORCID 0000-0001-7469-4752

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ongoing COVID-19 pandemic caused by SARS-CoV-2 is associated with high morbidity and mortality. This zoonotic virus has emerged in Wuhan of China in December 2019 from bats and pangolins probably and continuing the human-to-human transmission globally since last two years. As there is no efficient approved treatment, a number of vaccines were developed at an unprecedented speed to counter the pandemic. Moreover, vaccine hesitancy is observed that may be another possible reason for this never ending pandemic. In the meantime, several variants and mutations were identified and causing multiple waves globally. Now the safety and efficacy of these vaccines are debatable and recommended to determine whether vaccines are able to interrupt transmission of SARS-CoV-2 variant of concern (VOC). Moreover, the VOCs continue to emerge that appear more transmissible and less sensitive to virus-specific immune responses. In this overview, we have highlighted various drugs and vaccines used to counter this pandemic along with their reported side effects. Moreover, the preliminary data for the novel VOC "Omicron" are discussed with the existing animal models.

Indexed as

COVID-19VaccinesAnimalsHumansPandemicsSARS-CoV-2Vaccinesanimal modelsdrugs and vaccinesSARS-CoV-2 VOCsvaccine effectivenessvaccine hesitancyvaccine side effects

Identifiers

PMID35184391
PMCPMC9111768

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.