Evidence map›Paper›PMID 35184026›Full record

ReviewDevelopmental cognitive neuroscience2022

An ode to fetal, infant, and toddler neuroimaging: Chronicling early clinical to research applications with MRI, and an introduction to an academic society connecting the field.

Angeliki Pollatou, Courtney A Filippi, Ezra Aydin, Kelly Vaughn, Deanne Thompson, Marta Korom, Alexander J Dufford, Brittany Howell, Lilla Zöllei, Adriana Di Martino and 4 more

Abstract readReview
In one paragraph

Review in Developmental cognitive neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Social Determinants of Health, the developing brain, and risk and resilience for psychopathology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  6. Review
  7. Review
  8. Review
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  10. Article
  11. Review
  12. Applying fetal, infant, and toddler (FIT) neuroimaging to understand mental health.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  13. Article
  14. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Angeliki PollatouDepartment of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.
Courtney A FilippiSection on Development and Affective Neuroscience, National Institute of Mental Health, Bethesda, MD, USA; Department of Human Development and Quantitative Methodology, University of Maryland, College Park, MD, USA.
Ezra AydinDepartment of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA; Department of Psychology, University of Cambridge, Cambridge, UK.
Kelly VaughnDepartment of Pediatrics, University of Texas Health Sciences Center, Houston, TX, USA.
Deanne ThompsonClinical Sciences, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Marta KoromDepartment of Psychological and Brain Sciences, University of Delaware, Newark, DE, USA.
Alexander J DuffordDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Brittany HowellFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA, USA; Department of Human Development and Family Science, Virginia Tech, Blacksburg, VA, USA.
Lilla ZölleiLaboratory for Computational Neuroimaging, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.
Adriana Di MartinoChild Mind Institute, New York, NY, USA.
Alice GrahamDepartment of Psychiatry, Oregon Health and Science University, Portland, OR, USA.
FIT’NG Group
Dustin ScheinostDepartment of Psychological and Brain Sciences, University of Delaware, Newark, DE, USA; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA; Yale Child Study Center, Yale School of Medicine, New Haven, CT, USA.
Marisa N SpannDepartment of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA; Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA. Electronic address: mns2125@cumc.columbia.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Fmri Studies Of Risk For Mood And Anxiety Disorders In ChildrenZIAMH002782 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$28.3M
The integrated Translational Health Research Institute of Virginia (iTHRIV): Using Data to Improve HealthUL1TR003015 · NCATS · UNIVERSITY OF VIRGINIA · PI BROWN, DONALD E, JOHNSTON, KAREN C. · 2019 to 2023
$20.3M
TRAINING PROGRAM IN CHILDHOOD NEUROPSYCHIATRIC DISORDERST32MH018268 · NIMH · YALE UNIVERSITY · PI Michael H Bloch, MICHAEL J CROWLEY · 1985 to 2026
$11.0M
NRSA Training CoreTL1TR001875 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SPANN, MARISA N, TAYLOR, JACQUELYN Y · 2016 to 2025
$8.9M
Longitudinal Study of childhood fMRI markers prior to reading onsetR01HD065762 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI GAAB, NADINE, GRANT, PATRICIA ELLEN · 2011 to 2021
$6.3M
INTERGENERATIONAL TRANSMISSION OF DEFICITS IN SELF-REGULATORY CONTROLR01MH117983 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARSH, RACHEL, MONK, CATHERINE E · 2018 to 2022
$4.0M
Institutional Career Development CoreKL2TR003016 · NCATS · UNIVERSITY OF VIRGINIA · PI PAPIN, JASON, WORRALL, BRADFORD B · 2019 to 2023
$3.9M
A Randomized Control Trial of a Responsive Parenting Intervention to Support Healthy Brain Development and Self-regulation in Toddlers Born PretermR01HD100560 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BICK, JOHANNA RENEE, DEMASTER, DANA MCKENNA · 2020 to 2024
$3.3M
Neuroimaging and gut microbiome markers of development in HIV-exposed uninfected infantsR01HD093578 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI HOLMES, MARTHA, KABA, MAMADOU · 2017 to 2022
$2.9M
Extension of a longitudinal cognitive and brain imaging study of early-treated perinatally HIV infected children through adolescenceR01HD099846 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI LAUGHTON, BARBARA, MEINTJES, ERNESTA MARIA · 2019 to 2023
$2.7M
Intramural NIH HHS ZIA MH002782NCATS NIH HHS KL2 TR003016NCATS NIH HHS TL1 TR001875NCATS NIH HHS UL1 TR001863NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR003015NIBIB NIH HHS R03 EB022754NICHD NIH HHS R01 HD065762NICHD NIH HHS R01 HD093578NICHD NIH HHS R01 HD099846NICHD NIH HHS R01 HD100560NICHD NIH HHS R21 HD095338NIDA NIH HHS R34 DA050291NIMH NIH HHS K24 MH127381NIMH NIH HHS R01 MH117983NIMH NIH HHS T32 MH018268
6 · The paper itself

Abstract

Fetal, infant, and toddler neuroimaging is commonly thought of as a development of modern times (last two decades). Yet, this field mobilized shortly after the discovery and implementation of MRI technology. Here, we provide a review of the parallel advancements in the fields of fetal, infant, and toddler neuroimaging, noting the shifts from clinical to research use, and the ongoing challenges in this fast-growing field. We chronicle the pioneering science of fetal, infant, and toddler neuroimaging, highlighting the early studies that set the stage for modern advances in imaging during this developmental period, and the large-scale multi-site efforts which ultimately led to the explosion of interest in the field today. Lastly, we consider the growing pains of the community and the need for an academic society that bridges expertise in developmental neuroscience, clinical science, as well as computational and biomedical engineering, to ensure special consideration of the vulnerable mother-offspring dyad (especially during pregnancy), data quality, and image processing tools that are created, rather than adapted, for the young brain.

Indexed as

Magnetic Resonance ImagingNeuroimagingBrainChild, PreschoolFemaleHumansInfantLongitudinal StudiesPregnancyPrenatal CareBrain developmentFetal neuroimagingFIT’NGFMRIInfant neuroimagingLongitudinal studiesMRI

Identifiers

PMID35184026
PMCPMC8861425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.