Evidence map›Paper›PMID 35184004›Full record

Trial reportAddictive behaviors2022

Acute alcohol rewarding effects as a risk factor for hangover frequency.

Jesus Chavarria, Daniel J Fridberg, Andrea C King

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Addictive behaviors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Jesus ChavarriaCentre for Addiction and Mental Health, 100 Collip Cir. Suite 200, London, ON N6G 4X8, Canada. Electronic address: jesus.chavarria@camh.ca.
Daniel J FridbergDepartment of Psychiatry & Behavioral Neuroscience, University of Chicago, 5841 S. Maryland Avenue MC-3077, Chicago, IL 60637, United States.
Andrea C KingDepartment of Psychiatry & Behavioral Neuroscience, University of Chicago, 5841 S. Maryland Avenue MC-3077, Chicago, IL 60637, United States. Electronic address: aking@bsd.uchicago.edu.
University of Chicago · USCentre for Addiction and Mental Health · CA

Funding

Alcohol Stimulation and Sedation in Binge Drinkers - Renewal 01R01AA013746 · NIAAA · UNIVERSITY OF CHICAGO · PI DANIEL J FRIDBERG, ANDREA C KING · 2003 to 2026
$11.6M
NIAAA NIH HHS R01 AA013746
6 · The paper itself

Abstract

background/purposeAcute subjective alcohol effects appear to play an important role in predicting alcohol hangover. However, no studies have used a laboratory-based alcohol challenge to examine the concurrent or longitudinal effects of subjective alcohol responses on hangover frequency. As such, we investigated the direct and indirect effects of alcohol stimulation, sedation, liking and wanting, as measured in a controlled setting, on hangover frequency over five years.

methodParticipants were 294 young adult light-to-heavy social drinkers (aged 21-35 years, 42% female) enrolled in the Chicago Social Drinking Project. The study utilized a placebo-controlled, double blind, laboratory alcohol challenge and a battery of measures including the Biphasic Alcohol Effects Scale, Drug Effects Questionnaire, Hangover Symptom Scale, and alcohol use Quantity-Frequency Interview, with the latter two re-administered after five years.

resultsThrough the use of a path analysis, the present study found significant direct effects from alcohol liking to hangover frequency at initial testing. In addition, there were multiple significant indirect effects from greater alcohol liking and wanting to greater alcohol use quantity-frequency and, in turn, greater hangover frequency at initial testing and 5-year follow-up. Last, there were significant indirect effects from greater alcohol sedation to less alcohol use quantity-frequency and, in turn, less hangover frequency at initial testing and 5-year follow-up.

conclusionThis study highlights the role of the hedonic reward and motivational salience of alcohol as potential mechanisms of alcohol-related consequences (i.e., hangover) among light-to-heavy social drinking young adults.

Indexed as

Alcohol DrinkingAlcoholic IntoxicationAdultEthanolFemaleHumansMaleRewardRisk FactorsYoung AdultEthanolAlcohol rewardAlcohol use frequencyAlcohol use quantityHangoversSubjective alcohol responses

Identifiers

PMID35184004
PMCPMC8966905
OpenAlexW4211140189

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.