Evidence map›Paper›PMID 35183621›Full record

ArticleJournal of affective disorders2022

Cross-country variations in the reporting of psychotic symptoms among sub-Saharan African adults: A psychometric evaluation of the Psychosis Screening Questionnaire.

Mary Bitta, Yanga Thungana, Hannah H Kim, Christy A Denckla, Amantia Ametaj, Mahlet Yared, Claire Kwagala, Linnet Ongeri, Rocky E Stroud, Edith Kwobah and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Psychometric evaluation of the psychosis screening questionnaire in South Africa with attention to overlap between symptoms and normative cultural beliefs.World cultural psychiatry research review : official journal of World Association of Cultural Psychiatry · 2023
    Article
  7. Psychosis screening questionnaire: Exploring its factor structure among South African adults.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Mary BittaClinical Research-Neurosciences, KEMRI/Wellcome Trust Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya; Department of Psychiatry, University of Oxford, Oxford, UK. Electronic address: mbitta@kemri-wellcome.org.
Yanga ThunganaDepartment of Psychiatry, Walter Sisulu University, Mthatha, South Africa.
Hannah H KimDepartment of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Christy A DencklaDepartment of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Amantia AmetajDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Mahlet YaredDepartment of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Claire KwagalaDepartment of Psychiatry, Makerere University, Kampala, Uganda.
Linnet OngeriDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Rocky E StroudDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Edith KwobahDepartment of Mental Health, Moi teaching and Referral Hospital, Eldoret, Kenya.
Karestan C KoenenDepartment of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Symon KariukiClinical Research-Neurosciences, KEMRI/Wellcome Trust Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya.
Zukiswa ZingelaDepartment of Psychiatry, Walter Sisulu University, Mthatha, South Africa.
Dickens AkenaDepartment of Psychiatry, Makerere University, Kampala, Uganda.
Charles NewtonClinical Research-Neurosciences, KEMRI/Wellcome Trust Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya; Department of Psychiatry, University of Oxford, Oxford, UK.
Lukoye AtwoliDepartment of Mental Health, Moi teaching and Referral Hospital, Eldoret, Kenya; Medical College East Africa, The Aga Khan University, Nairobi, Kenya.
Solomon TeferraDepartment of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Dan J SteinSA MRC Unit on Risk & Resilience in Mental Disorders, Dept of Psychiatry & Neuroscience Institute, University of Cape Town, Cape Town, South Africa.
Bizu GelayeDepartment of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, Cambridge, MA, USA; The Chester M. Pierce, MD Division of Global Psychiatry, Massachusetts General Hospital, Boston, MA, USA.

Funding

1/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African AncestriesU01MH125047 · NIMH · BROAD INSTITUTE, INC. · PI MARTIN, ALICIA, NEALE, BENJAMIN MICHAEL · 2020 to 2024
$11.5M
Training Program in Psychiatric Genetics and Translational ResearchT32MH017119 · NIMH · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI KARESTAN C KOENEN, Jukka-Pekka Onnela · 1985 to 2026
$8.9M
2/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African AncestriesU01MH125045 · NIMH · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI KOENEN, KARESTAN C · 2020 to 2024
$3.1M
Psychosis Genetics Research in Africa: Building Capacity by Investing in PeopleR01MH120642 · NIMH · BROAD INSTITUTE, INC. · PI AKENA, DICKENS HOWARD, CHIBNIK, LORI BETH · 2019 to 2023
$3.1M
Pathogenic mechanisms in post-bereavement psychopathology: Contributions of gene-environment interplay, psychosocial factors, and cognitive ability in two population-based cohortsK23MH117278 · NIMH · HARVARD SCHOOL OF PUBLIC HEALTH · PI DENCKLA, CHRISTY ANN · 2019 to 2023
$942k
NIMH NIH HHS K23 MH117278NIMH NIH HHS R01 MH120642NIMH NIH HHS T32 MH017119NIMH NIH HHS U01 MH125045NIMH NIH HHS U01 MH125047
6 · The paper itself

Abstract

backgroundSelf-reporting of psychotic symptoms varies significantly between cultures and ethnic groups. Yet, limited validated screening instruments are available to capture such differences in the African continent. METHODOLOGY: Among 9,059 individuals participating as controls in a multi-country case-control study of the genetic causes of psychosis, we evaluated the psychometric properties of the Psychosis Screening Questionnaire (PSQ). We applied multi-group confirmatory factor analysis and item response theory to assess item parameters.

resultsThe overall positive endorsement of at least one item assessing psychotic symptoms on the PSQ was 9.7%, with variability among countries (Uganda 13.7%, South Africa 11%, Kenya 10.2%, and Ethiopia 2.8%). A unidimensional model demonstrated good fit for the PSQ (root mean square error of approximation = 0.009; comparative fit index = 0.997; and Tucker-Lewis Index = 0.995). Hypomania had the weakest association with single latent factor (standardized factor loading 0.62). Sequential multi-group confirmatory factor analysis demonstrated that PSQ items were measured in equivalent ways across the four countries. PSQ items gave more information at higher levels of psychosis, with hypomania giving the least discriminating information. LIMITATIONS: Participants were recruited from general medical facilities, so findings may not be generalizable to the general population.

conclusionThe PSQ demonstrated a unidimensional factor structure in these samples. Items were measured equivalently across all study settings, suggesting that differences in prevalence of psychotic symptoms between countries were less likely to represent measurement artifact. The PSQ is more reliable in screening for psychosis in individuals with higher degrees of psychotic experiences-hypomania excluded-and might decrease the false-positive rate from mild nonspecific psychotic experiences.

Indexed as

Psychotic DisordersAdultCase-Control StudiesEthiopiaHumansPsychometricsReproducibility of ResultsSurveys and QuestionnairesassessmentPsychosisscreeningsub-Saharan Africa

Identifiers

PMID35183621
PMCPMC9036658

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.