SynthesisPreventive medicine2022
Willingness, refusal and influential factors of parents to vaccinate their children against the COVID-19: A systematic review and meta-analysis.
Synthesis in Preventive medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 12 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
109 citing papers in PubMed, 12 syntheses or guidelines pooled it, 154 citations in OpenAlex.
- Factors ınfluencing vaccine refusal in children: an umbrella review on COVID-19 and childhood vaccinations.BMC public health · 2026Pooled it
- Pooled it
- COVID-19 Vaccine Acceptance and Hesitancy among People Living with HIV: Review and Meta-Analysis.AIDS and behavior · 2024Pooled it
- COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis.JMIR public health and surveillance · 2024Pooled it
- A systematic review and meta-analysis of the global prevalence and determinants of COVID-19 vaccine acceptance and uptake in people living with HIV.Nature human behaviour · 2024Pooled it
- COVID-19 vaccination hesitancy among Italian parents: A systematic review and meta-analysis.Human vaccines & immunotherapeutics · 2023Pooled it
- Immunogenicity, effectiveness, and safety of COVID-19 vaccines among children and adolescents aged 2-18 years: an updated systematic review and meta-analysis.World journal of pediatrics : WJP · 2023Pooled it
- Key factors influencing paediatric COVID-19 vaccine hesitancy: a brief overview and Decision-making Trial and Evaluation Laboratory analysis.Public health · 2023Pooled it
- COVID-19 vaccine hesitancy among parents in Low- and Middle-Income Countries: A meta-analysis.Frontiers in public health · 2023Pooled it
- The determinants of COVID-19 vaccination intention: a meta-review.Frontiers in public health · 2023Pooled it
- Chinese parents' willingness to vaccinate their children against COVID-19: A systematic review and meta-analysis.Frontiers in public health · 2022Pooled it
- Pooled it
- Using positive imagination to reduce negativity in information processing and hesitant attitudes towards childhood COVID-19 vaccinations in parents: A randomized controlled trial.British journal of health psychology · 2025Trial
- Article
- A Cross-Sectional Study Examining Vaccine Uptake and Attitudes Among Parents Compared to Other Adults.Health education & behavior : the official publication of the Society for Public Health Education · 2026Article
- Critical Evaluation of the Impact of COVID-19 Pandemic on Child Health and Wellbeing and Suggested Preparedness for Future Pandemics-A Narrative Review.Health science reports · 2026Article
- Article
- Beyond binary: a machine-learning classification of childhood COVID-19 vaccination intentions using behavioural data.Population health metrics · 2025Article
- Article
- COVID-19 vaccine confidence among parents of racially diverse children aged 0-12 years old in Canada: The role of major experience of racial discrimination, health literacy, and conspiracy beliefs.Human vaccines & immunotherapeutics · 2025Article
49 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to estimate parents' willingness and refusal to vaccinate their children against the COVID-19, and to investigate the predictors for their decision. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. We searched Scopus, Web of Science, Medline, PubMed, CINAHL and medrxiv from inception to December 12, 2021. We applied a random effect model to estimate pooled effects since the heterogeneity was very high. We used subgroup analysis and metaregression analysis to explore sources of heterogeneity. We found 44 studies including 317,055 parents. The overall proportion of parents that intend to vaccinate their children against the COVID-19 was 60.1%, while the proportion of parents that refuse to vaccinate their children was 22.9% and the proportion of unsure parents was 25.8%. The main predictors of parents' intention to vaccinate their children were fathers, older age of parents, higher income, higher levels of perceived threat from the COVID-19, and positive attitudes towards vaccination (e.g. children's complete vaccination history, history of children's and parents' vaccination against influenza, confidence in vaccines and COVID-19 vaccines, and COVID-19 vaccine uptake among parents). Parents' willingness to vaccinate their children against the COVID-19 is moderate and several factors affect this decision. Understanding parental COVID-19 vaccine hesitancy does help policy makers to change the stereotypes and establish broad community COVID-19 vaccination. Identification of the factors that affect parents' willingness to vaccinate their children against COVID-19 will provide opportunities to enhance parents' trust in the COVID-19 vaccines and optimize children's uptake of a COVID-19 vaccine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.