Observational studyJACC. Cardiovascular imaging2022
Thoracic Aortic
Open access · hybridAbstract readObservational Study
In one paragraph
Observational study in JACC. Cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 38 citations in OpenAlex.
- Effect of Denosumab or Alendronate on Vascular Calcification: Secondary Analysis of SALTIRE2 Randomized Controlled Trial.Journal of the American Heart Association · 2024Trial
- Cardiovascular imaging with total-body PET.The British journal of radiology · 2026Review
- Review
- Gene expression profiles of carotid plaques differ between patients with amaurosis fugax and those with cerebral transient ischaemic attack or stroke.Cardiovascular research · 2026Article
- Calcific Aortopathy in Response to Aging and Injury.Circulation · 2026Review
- Aortic Atherosclerosis: An Updated Review of Current Guidelines and Management Approach-A Literature Review.The International journal of angiology : official publication of the International College of Angiology, Inc · 2026Article
- Reproducibility ofCurrent cardiology reports · 2025Review
- Emerging Applications of Positron Emission Tomography in Coronary Artery Disease.Journal of personalized medicine · 2025Review
- Quantitative aortic Na[European journal of nuclear medicine and molecular imaging · 2025Article
- Sex differences in coronary atherosclerotic plaque activity usingEuropean journal of nuclear medicine and molecular imaging · 2024Article
- Uncovering atherosclerotic cardiovascular disease by PET imaging.Nature reviews. Cardiology · 2024Review
- Thoracic aortic microcalcification activity in combined positron emission tomography and magnetic resonance imaging.European journal of nuclear medicine and molecular imaging · 2024Article
- Noninvasive Atherosclerotic Phenotyping: The Next Frontier into Understanding the Pathobiology of Coronary Artery Disease.Current atherosclerosis reports · 2024Review
- Thoracic Aortic Plaque Burden and Prediction of Cardiovascular Events in Patients Undergoing 320-row Multidetector CT Coronary Angiography.Journal of atherosclerosis and thrombosis · 2024Article
- Aortic sodium [Heart (British Cardiac Society) · 2023Article
- Hypertension-mediated organ damage involving multiple sites is an independent risk factor for cardiovascular events.European heart journal open · 2023Article
- Multimodality Imaging of Aortic Valve Calcification and Function in a Murine Model of Calcific Aortic Valve Disease and Bicuspid Aortic Valve.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023Article
- The Role of Positron Emission Tomography in Advancing the Understanding of the Pathogenesis of Heart and Vascular Diseases.Diagnostics (Basel, Switzerland) · 2023Review
- Advanced Cardiac Imaging in the Assessment of Aortic Stenosis.Journal of cardiovascular development and disease · 2023Review
- Advances in the Assessment of Coronary Artery Disease Activity with PET/CT and CTA.Tomography (Ann Arbor, Mich.) · 2023Review
Corrections and comments
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Authors and funding
25 authors at 6 institutions in 4 countries.
Alexander J FletcherBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Yong Y TewBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Evangelos TzolosBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Shruti S JoshiBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Jakub KaczynskiBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Jennifer NashBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Samuel DebonoBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Maria LemboBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom; Department of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy.
Jacek KwiecinskiDepartment of Interventional Cardiology and Angiology, Institute of Cardiology, Warsaw, Poland.
Rong BingBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Maaz B J SyedBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Mhairi K DorisBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Edwin J R van BeekBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom; Edinburgh Imaging Facility, Queens Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Alistair J MossBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
William S JenkinsBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Niki L WalkerBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom; Scottish Adult Congenital Cardiology Service, Golden Jubilee National Hospital, Clydebank, Glasgow, United Kingdom.
Nikhil V JoshiBristol Heart Institute, Bristol Royal Infirmary, University of Bristol, United Kingdom.
Tania A PawadeBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Philip D AdamsonChristchurch Heart Institute, University of Otago, Christchurch, New Zealand.
William N WhiteleyCentre for Clinical Brain Sciences, UK Dementia Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Joanna M WardlawEdinburgh Imaging Facility, Queens Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom; Centre for Clinical Brain Sciences, UK Dementia Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Piotr J SlomkaCedars-Sinai Medical Centre, Department of Imaging (Division of Nuclear Cardiology), Los Angeles, USA.
Michelle C WilliamsBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
David E NewbyBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom; Edinburgh Imaging Facility, Queens Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Marc R DweckBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom. Electronic address: Marc.dweck@ed.ac.uk.
University of Edinburgh · GBBritish Heart Foundation · GBBristol Royal Infirmary · GBInstitute of Cardiology · PLUniversity of Naples Federico II · ITUniversity of Otago · NZ
Funding
Integrated analysis of coronary anatomy and biology with 18F-fluoride PET and CT angiographyR01HL135557 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI SLOMKA, PIOTR J · 2017 to 2020
$3.0MBritish Heart Foundation CH/09/002/26360British Heart Foundation FS/14/78/31020British Heart Foundation FS/17/50/33061British Heart Foundation FS/17/51/33096British Heart Foundation FS/17/79/33226British Heart Foundation FS/18/31/33676British Heart Foundation FS/19/15/34155British Heart Foundation FS/CRTF/20/24087British Heart Foundation FS/ICRF/20/26002British Heart Foundation RG/16/10/32375Medical Research Council G0701127Medical Research Council MR/T005459/1NHLBI NIH HHS R01 HL135557
Abstract
backgroundAortic atherosclerosis represents an important contributor to ischemic stroke risk. Identifying patients with high-risk aortic atheroma could improve preventative treatment strategies for future ischemic stroke.
objectivesThe purpose of this study was to investigate whether thoracic
methodsIn a post hoc observational cohort study, we quantified thoracic aortic and coronary
resultsAfter 12.7 ± 2.7 months, progression of thoracic aortic calcium volume correlated with baseline thoracic aortic
conclusionsIn patients with established cardiovascular disease, thoracic aortic
Indexed as
Aortic Valve StenosisAtherosclerosisCardiovascular DiseasesMyocardial InfarctionPlaque, AtheroscleroticStrokeCalciumFluorine RadioisotopesHumansPositron Emission Tomography Computed TomographyPredictive Value of TestsRadiopharmaceuticalsSodium FluorideCalciumFluorine RadioisotopesRadiopharmaceuticalsSodium Fluoride(18)F-sodium fluoridecalcificationcomputed tomographypositron emission tomographystrokethoracic aorta
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.