Evidence map›Paper›PMID 35183411›Full record

SynthesisEuropean journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology2022

Fit4Surgery for cancer patients during covid-19 lockdown - A systematic review and meta-analysis.

T van Gestel, L C B Groen, J R Puik, S J van Rooijen, H J van der Zaag-Loonen, L J Schoonmade, G Danjoux, F Daams, W H Schreurs, E R J Bruns

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Preoperative prehabilitation in adults: A concept analysis.International journal of nursing studies advances · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Perspectives on the Direction of Cancer Prehabilitation in the Pandemic and Beyond.Archives of rehabilitation research and clinical translation · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

T van GestelDepartment of Surgery, Northwest Clinics, Alkmaar, the Netherlands. Electronic address: tvgestel@diakhuis.nl.
L C B GroenDepartment of Surgery, Northwest Clinics, Alkmaar, the Netherlands.
J R PuikDepartment of Surgery, Amsterdam University Medical Center Location VU, Amsterdam, the Netherlands.
S J van RooijenCare and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands.
H J van der Zaag-LoonenDepartment of Epidemiology, University Medical Center Groningen, Groningen, the Netherlands.
L J SchoonmadeMedical Library, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
G DanjouxSouth Tees Hospitals NHS Foundation Trust, UK; Honorary Professor, Hull York Medical School and Teesside University, UK.
F DaamsDepartment of Surgery, Amsterdam University Medical Center Location VU, Amsterdam, the Netherlands.
W H SchreursDepartment of Surgery, Northwest Clinics, Alkmaar, the Netherlands.
E R J BrunsDepartment of Surgery, Northwest Clinics, Alkmaar, the Netherlands.
Northwest Hospital · USAmsterdam University Medical Centers · NLMaastricht University · NLSouth Tees Hospitals NHS Foundation Trust · GBUniversity Medical Center Groningen · NLVrije Universiteit Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrehabilitation is a promising method to enhance postoperative recovery, especially in patients suffering from cancer. Particularly during times of social distancing, providing home-based programmes may have become a suitable solution to increase compliance and effectiveness.

methodsIn line with the PRISMA guidelines, a systematic review was conducted including trials that investigated the effect of home-based prehabilitation (HBP) in patients undergoing surgery for cancer. The primary outcome was postoperative functional capacity (6 min walk test, 6MWT). Secondary outcomes were postoperative complications and compliance.

resultsFive randomized controlled trials were included with 351 patients undergoing surgery for colorectal cancer, oesophagogastric cancer, bladder cancer and non-small cell lung cancer. Three studies presented results of significant progress after eight weeks. The meta-analysis showed a significant improvement of the 6MWT in the prehabilitation group compared to the control group preoperatively (MD 35.06; 95% CI 11.58 to 58.54; p = .003) and eight weeks postoperatively (MD 44.91; 95% CI 6.04 to 83.79; p = .02) compared to baseline. Compliance rate varied from 63% to 83% with no significant difference between prehabilitation and control groups. These data must be interpreted with caution because of a high amount of heterogeneity and small sample sizes. DISCUSSION: In conclusion, HBP may enhance overall functional capacity of patients receiving oncological surgery compared to standard of care. This could be a promising alternative to hospital-based prehabilitation regarding the current pandemic and further digitalization in the future. In order to increase accessibility and effectiveness of prehabilitation, home-based solutions should be further investigated.

Indexed as

Carcinoma, Non-Small-Cell LungColorectal NeoplasmsCOVID-19Lung NeoplasmsCommunicable Disease ControlHumansPostoperative ComplicationsPreoperative CareCancerExercise therapy and clinical trialsPrehabilitationSurgery

Identifiers

PMID35183411
PMCPMC8828288
OpenAlexW4210944310

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.