Evidence map›Paper›PMID 35183238›Full record

Trial reportTrials2022

Animated, video entertainment-education to improve vaccine confidence globally during the COVID-19 pandemic: an online randomized controlled experiment with 24,000 participants.

Simiao Chen, Sebastian Forster, Juntao Yang, Fengyun Yu, Lirui Jiao, Jennifer Gates, Zhuoran Wang, Haitao Liu, Qiushi Chen, Pascal Geldsetzer and 5 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07512375 (Efficacité d'un Programme d'ETP Dans la myasthénie), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07512375 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Efficacité d'un Programme d'ETP Dans la myasthénie : étude de Preuve de Principe (MY-EDUC).

TypeobservationalSponsorUniversity Hospital, GrenobleRan2026 to 2027Enrolled62ConditionsMyasthenia Gravis (MG)ArmsCBSM
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  2. Trial
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Simiao ChenHeidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany. simiao.chen@uni-heidelberg.de.ORCID http://orcid.org/0000-0003-0555-2157
Sebastian ForsterHeidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany.
Juntao YangState Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Fengyun YuDepartment of Industrial Engineering, Tsinghua University, Beijing, China.
Lirui JiaoReed College, Portland, OR, USA.
Jennifer GatesIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Zhuoran WangChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Haitao LiuChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Qiushi ChenThe Harold and Inge Marcus Department of Industrial and Manufacturing Engineering, The Pennsylvania State University, University Park, PA, USA.
Pascal GeldsetzerDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Peixin WuChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chen WangChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Shannon McMahonHeidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany.
Till BärnighausenHeidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany.
Maya AdamDepartment of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.

Funding

Chinesisch-Deutsche Zentrum für Wissenschaftsförderung Project C-0048
6 · The paper itself

Abstract

backgroundScience-driven storytelling and entertainment-education (E-E) media demonstrate potential for promoting improved attitudes and behavioral intent towards health-related practices. Months after the outbreak of coronavirus disease 2019 (COVID-19), emerging research highlights the essential role of interventions to improve public confidence in the COVID-19 vaccine. To improve vaccine confidence, we designed three short, animated videos employing three research-informed pedagogical strategies. These can be distributed globally through social media platforms, because of their wordless and culturally accessible design. However, the effectiveness of short, animated storytelling videos, deploying various pedagogic strategies, needs to be explored across different global regions. METHODS/

designThe present study is a multi-site, parallel group, randomized controlled trial (RCT) comparing the effectiveness of (i) a storytelling-instructional-humor approach, (ii) a storytelling-analogy approach, (iii) a storytelling-emotion-focused approach, and (iv) no video. For our primary outcomes, we will measure vaccine hesitancy, and for secondary outcomes, we will measure behavioral intent to seek vaccination and hope. Using online platforms, we will recruit 12,000 participants (aged 18-59 years) from the USA and China, respectively, yielding a total sample size of 24,000. DISCUSSION: This trial uses innovative online technology, reliable randomization algorithms, validated survey instruments, and list experiments to establish the effectiveness of three short, animated videos employing various research-informed pedagogical strategies. Results will be used to scientifically support the broader distribution of these short, animated video as well as informing the design of future videos for rapid, global public health communication.

trial registrationGerman Clinical Trials Register DRKS #00023650 . Date of registration: 2021/02/09.

Indexed as

COVID-19Social MediaVaccinesAdolescentAdultHumansMiddle AgedPandemicsSARS-CoV-2Young AdultVaccinesCOVID-19HopeList experimentProtocolRrandomized controlled trialVaccine acceptanceVaccine confidenceVaccine hesitancy

Identifiers

PMID35183238
PMCPMC8857749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.