ArticleVeterinary medicine and science2022
In vitro antibacterial and antifungal activities of extracts and fractions of leaves of Ricinus communis Linn against selected pathogens.
Article in Veterinary medicine and science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Antibacterial activity of medicinal plants on the management of mastitis in dairy cows: A systematic review.Veterinary medicine and science · 2023Pooled it
- Lactobacilli Isolated from the Caecum of Healthy Broilers with Antimicrobial Activity are Probiotic Candidates for Controlling Salmonella.Probiotics and antimicrobial proteins · 2026Article
- Phytochemical profiling and in-vitro antibacterial activity of Croton macrostachyus Hochst. ex Delile leaf and stem bark extracts against selected human pathogens.Scientific reports · 2026Article
- Synthesis, Characterization, and Colorimetric Sensing of ZrChemistry, an Asian journal · 2026Article
- Antibacterial Activity, Phytochemical Composition, and Cytotoxicity Evaluation of Select Medicinal Plants from Bangladesh.Current microbiology · 2025Article
- Review
- Morphological and Molecular Identification ofClinical case reports · 2025Article
- Phytochemical screening and evaluating in vitro antibacterial and antifungal activity of 80% methanolic Impatiens rothii root extract.Scientific reports · 2025Article
- Evaluation of the antibacterial potential in shoot and root extracts of Eryngium campestre with emphasis on Egyptian ecotype.Scientific reports · 2025Article
- A Stroll Through Saffron Fields, Cannabis Leaves, and Cherry Reveals the Path to Waste-Derived Antimicrobial Bioproducts.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Antibacterial and Biopriming Effects of Nostocales Cyanobacteria on Tomato Plants Infected with Bacterial Spot Disease.Current microbiology · 2025Article
- Identification and Antimicrobial Potential of Marine Sponges (International journal of microbiology · 2025Article
- OverallFrontiers in microbiology · 2025Article
- In vitro antifungal activities of medicinal plants used for treatment of candidiasis in Pader district, Northern Uganda.Tropical medicine and health · 2024Article
- Biofilm inhibition of denture cleaning tablets and carvacrol on denture bases produced with different techniques.Clinical oral investigations · 2024Article
- The impact of Ricinus straw on tomato growth and soil microbial community.Frontiers in microbiology · 2024Article
- Expanded Therapeutic Applications ofCombinatorial chemistry & high throughput screening · 2024Review
- Impact ofPharmaceuticals (Basel, Switzerland) · 2023Article
- Bovine mastitis, a worldwide impact disease: Prevalence, antimicrobial resistance, and viable alternative approaches.Veterinary and animal science · 2023Review
- Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionInfectious disease impacts are reduced due to the development of antimicrobial agents. However, the effectiveness of antimicrobial agents is reduced over time because of the emergence of antimicrobial resistance. To overcome these problems, scholars have been searching for alternative medicines. Ricinus communis is used as a traditional treatment for bovine mastitis, wound infection, and other medicinal purposes.
objectiveThe objective of the present study was to further evaluate the antimicrobial activities of R. communis leaf extracts and fractions.
methodsR. communis leaves were macerated in methanol and acetone. The methanol extract showed better antimicrobial activity and subjected to further fractionation via increasing polarity of solvents (n-hexane, chloroform, ethyl acetate, and aqueous). Test microorganisms included in the study were six laboratory reference bacteria (Escherichia coli, Staphylococcus aureus, Streptococcus agalactiae, Kleibsella pneumoniae, Pseudomonas aeruginosa and Streptococcus pyogenes), two clinical isolate bacteria (E. coli and S. aureus), and Candida albicans. The agar well diffusion method was employed to determine antimicrobial activity. The minimum inhibitory concentrations (MIC) and minimum bactericidal/fungicidal concentrations (MBC/MFC) were determined through broth microdilution.
resultsThe results indicated that the best antimicrobial activity for ethyl acetate fraction ranged from 14.67 mm (clinical E. coli) to 20.33 mm (S. aureus) at 400 mg/ml, however, n-hexane exhibited the lowest antimicrobial activity. Among the tested fractions, ethyl acetate fraction showed the lowest MIC values ranged from 1.5625 mg/ml (S. aureus) to 16.67 mg/ml (Candida albicans). The ethyl acetate fraction showed bactericidal activity against all tested microorganisms.
conclusionHence, ethyl acetate fraction of crude methanol extract exhibited the best antimicrobial activity.
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