Evidence map›Paper›PMID 35182352›Full record

Trial reportAging clinical and experimental research2022

Psychosocial determinants for adherence to a healthy lifestyle and intervention participation in the FINGER trial: an exploratory analysis of a randomised clinical trial.

Elisa Neuvonen, Jenni Lehtisalo, Alina Solomon, Riitta Antikainen, Satu Havulinna, Tuomo Hänninen, Tiina Laatikainen, Jaana Lindström, Nina Rautio, Hilkka Soininen and 4 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01041989 (Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01041989 naunknown statusnot on this map

Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability

TypeinterventionalSponsorFinnish Institute for Health and WelfareRan2009 to 2025Enrolled1,200ConditionsCognitive Impairment, DementiaArmsNutritional guidance, Exercise, Cognitive training, Reduction of vascular risk factors
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elisa Neuvonen *School of Medicine, Institute of Clinical Medicine/Neurology, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland. elisa.neuvonen@uef.fi.ORCID http://orcid.org/0000-0002-1084-8393
Jenni Lehtisalo *School of Medicine, Institute of Clinical Medicine/Neurology, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland.
Alina SolomonSchool of Medicine, Institute of Clinical Medicine/Neurology, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland.
Riitta AntikainenCenter for Life Course Health Research/Geriatrics, University of Oulu, P.O. Box 5000, 90014, Oulu, Finland.
Satu HavulinnaAgeing, Disability and Functioning Unit, Finnish Institute for Health and Welfare, P.O. Box 30, 00271, Helsinki, Finland.
Tuomo HänninenDepartment of Neurology, Neurocenter, Kuopio University Hospital, P.O. Box 100, 70029 KYS, Kuopio, Finland.
Tiina LaatikainenPopulation Health Unit, Finnish Institute for Health and Welfare, P.O. Box 30, 00271, Helsinki, Finland.
Jaana LindströmPopulation Health Unit, Finnish Institute for Health and Welfare, P.O. Box 30, 00271, Helsinki, Finland.
Nina RautioCenter for Life Course Health Research/Geriatrics, University of Oulu, P.O. Box 5000, 90014, Oulu, Finland.
Hilkka SoininenSchool of Medicine, Institute of Clinical Medicine/Neurology, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland.
Timo StrandbergCenter for Life Course Health Research/Geriatrics, University of Oulu, P.O. Box 5000, 90014, Oulu, Finland.
Jaakko TuomilehtoPopulation Health Unit, Finnish Institute for Health and Welfare, P.O. Box 30, 00271, Helsinki, Finland.
Miia KivipeltoSchool of Medicine, Institute of Clinical Medicine/Neurology, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland.
Tiia NganduPopulation Health Unit, Finnish Institute for Health and Welfare, P.O. Box 30, 00271, Helsinki, Finland.

Funding

Academy of Finland 317465European Research Council 804371Suomalainen Tiedeakatemia 287490Suomalainen Tiedeakatemia 294061Suomalainen Tiedeakatemia 319318
6 · The paper itself

Abstract

BACKGROUND AND

aimsPsychosocial factors may affect adherence to lifestyle interventions and lifestyle changes. The role of psychosocial factors in dementia prevention needs more research. We aimed at clarify the issue in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER).

methodsThe population included 1260 participants aged 60-77 years at risk for cognitive decline, randomised to a multidomain lifestyle intervention or regular health advice for 2 years. Adherence was evaluated as participation in the provided activities and actual lifestyle changes, separately for each domain (diet, exercise, social/cognitive activity, vascular risk management) and combined into multidomain. Psychosocial factors were measured at trial baseline (depressive symptoms; study perception; health-related quality of life, HRQoL) and earlier life (hopelessness; satisfaction with family life, achievements, and financial situation).

resultsDepressive symptoms, hopelessness, and nonpositive study perception were negatively and HRQoL positively associated with participation in the multidomain intervention. Depressive symptoms, lower HRQoL, hopelessness and dissatisfaction with financial situation were associated with unhealthier lifestyles at baseline. Baseline depressive symptoms and lower HRQoL predicted less improvement in lifestyle, but did not modify the intervention effect on lifestyle change. DISCUSSION AND

conclusionsSeveral psychosocial factors were associated with participation in lifestyle intervention, while fewer of them contributed to lifestyle changes. Although the intervention was beneficial for lifestyle changes independent of psychosocial factors, those most in need of lifestyle improvement were less likely to be active. Tailoring lifestyle-modifying strategies based on the need for psychosocial support may add efficacy in future trials. TRIAL REGISTRY: ClinicalTrials.gov NCT01041989 2010-01-05.

Indexed as

Cognitive DysfunctionQuality of LifeAgedExerciseHealthy LifestyleHumansLife StyleAdherenceClinical trialDementia preventionLifestyleOlder adultsParticipationPsychosocial factors

Identifiers

PMID35182352
PMCPMC9283154

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.