Evidence map›Paper›PMID 35182295›Full record

ArticleMolecular diversity2022

DNA binding and cleavage, BRCA1 gene interaction, antiglycation and anticancer studies of transition metal complexes of sulfonamides.

Arusa Akhtar, Muhammad Danish, Awais Asif, Muhammad Nadeem Arshad, Abdullah M Asiri

Abstract read
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In one paragraph

Article in Molecular diversity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Arusa AkhtarDepartment of Chemistry, University of Gujrat, Hafiz Hayat Campus, Gujrat, 50700, Pakistan.
Muhammad DanishDepartment of Chemistry, University of Gujrat, Hafiz Hayat Campus, Gujrat, 50700, Pakistan. drdanish62@gmail.com.ORCID http://orcid.org/0000-0001-6361-4016
Awais AsifDepartment of Biochemistry, Nawaz Sharif Medical College, University of Gujrat, Gujrat, 50700, Pakistan. awais.asif@uog.edu.pk.
Muhammad Nadeem ArshadChemistry Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah, 21589, Saudi Arabia.
Abdullah M AsiriChemistry Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah, 21589, Saudi Arabia.
University of Gujrat · PKKing Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of 4-((4-methylphenylsulfonamido)methyl)cyclohexanecarboxylic acid (NaMSCCA) transition metal complexes [Cu(II), Zn(II), Ni(II), Mn(II), and Co(II)] have been synthesized by precipitation method. The characterization was done by physical techniques, FT-IR spectroscopy, mass spectrometry, and NMR spectroscopy. The molecular structures of nickel (II) AZ-3 and cobalt (II) AZ-5 complexes were determined by the X-ray diffraction technique and found to crystallize in the triclinic space group P-1. The coordination geometry around the central nickel (AZ-3) and cobalt (AZ-5) atoms was square planar bipyramidal. Molecular docking was performed with duplex DNA of sequence d(CGCGAATTCGCG)

Indexed as

Coordination ComplexesBRCA1 ProteinCobaltCopperDNAGenes, BRCA1HumansLigandsMolecular Docking SimulationNickelSpectroscopy, Fourier Transform InfraredSulfanilamideSulfonamidesBRCA1 ProteinBRCA1 protein, humanCobaltCoordination ComplexesCopperDNALigandsNickelSulfanilamideSulfonamidesAnticancerAntiglycation and antioxidantBRCA1 gene interactionDNA interactionTransition metal complexes

Identifiers

PMID35182295
OpenAlexW4212797587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.