Evidence map›Paper›PMID 35182276›Full record

ArticleBiochemical genetics2022

Estrogen Receptor Gene Polymorphism as a Possible Genetic Risk Factor for Treatment Response in ER-Positive Breast Cancer Patients.

Nasr M A Allahloubi, Abdel-Rahman N Zekri, Mohamed Ragab, Marwa Mohanad, Ola S Ahmed, Salem Eid, Mohamed Ghareeb, Iman Gouda, Abeer A Bahnassy

Abstract read
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In one paragraph

Article in Biochemical genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Nasr M A AllahloubiDepartment of Medical Oncology, National Cancer Institute, Cairo University, Giza, Egypt.
Abdel-Rahman N ZekriVirology and Immunology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Giza, Egypt.
Mohamed RagabMedical Oncology, Faculty of Medicine, Zagazig University, Zagagig, Egypt.
Marwa MohanadBiochemistry Department, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October, Giza, Egypt. marwamohanad@gmail.com.ORCID http://orcid.org/0000-0002-3827-9647
Ola S AhmedVirology and Immunology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Giza, Egypt.
Salem EidDepartment of Medical Oncology, National Cancer Institute, Cairo University, Giza, Egypt.
Mohamed GhareebDepartment of Medical Oncology, National Cancer Institute, Cairo University, Giza, Egypt.
Iman GoudaDepartment of Pathology, National Cancer Institute, Cairo University, Giza, Egypt.
Abeer A BahnassyTissue Culture and Cytogenetics Unit, Pathology Department, National Cancer Institute, Cairo University, Giza, Egypt.
Cairo University · EGMisr University for Science and Technology · EGZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estrogen receptor-α (ESR1) single nucleotide polymorphisms (SNPs) have been related to breast cancer (BC) susceptibility. In this retrospective study we investigated ESR1 SNPs in association with survival and treatment response in BC patients. Seven ESR1 SNPs were genotyped using TaqMan probe assay in 100 formalin-fixed paraffin embedded blocks of Egyptian ER

Indexed as

Breast NeoplasmsReceptors, EstrogenAnthracyclinesEstrogen Receptor alphaFemaleHumansPolymorphism, Single NucleotideRetrospective StudiesRisk FactorsTamoxifenAnthracyclinesESR1 protein, humanEstrogen Receptor alphaReceptors, EstrogenTamoxifenESR1 polymorphismEstrogen receptor-positive breast cancerGenetic risk factorHormonal treatmentPrognosisResponse prediction

Identifiers

PMID35182276
OpenAlexW4213217332

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.