Evidence map›Paper›PMID 35182227›Full record

ArticleJournal of ophthalmic inflammation and infection2022

Coronavirus disease (COVID-19) and conjunctival sac swab findings.

Pavol Vesely, Elena Novakova, Michal Stubna, Michal Trnka, Denisa Jurenova, Darina Lyskova, Robert Furda, Paulina Plesnikova, Vratko Himic, Alena Furdova

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmic inflammation and infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Pavol VeselyDepartment of Ophthalmology, Faculty of Medicine, Comenius University, (Klinika oftalmológie LFUK a UNB), Hospital Ruzinov, Ružinovská 6, 826 06, Bratislava, Slovak Republic.
Elena NovakovaDepartment of Microbiology and Immunology, Jessenius Faculty of Medicine in Martin, Comenius University, Bratislava, Slovakia.
Michal StubnaDepartment of Ophthalmology, Hospital Zilina, Zilina, Slovakia.
Michal TrnkaDepartment of Medical Physics, Biophysics, Informatics and Telemedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Denisa JurenovaDepartment of Ophthalmology, Faculty of Medicine, Comenius University, (Klinika oftalmológie LFUK a UNB), Hospital Ruzinov, Ružinovská 6, 826 06, Bratislava, Slovak Republic.
Darina LyskovaDepartment of Ophthalmology, Faculty of Medicine, Comenius University, (Klinika oftalmológie LFUK a UNB), Hospital Ruzinov, Ružinovská 6, 826 06, Bratislava, Slovak Republic.
Robert FurdaDepartment of Information Systems, Faculty of Management, Comenius University in Bratislava, Bratislava, Slovakia.
Paulina PlesnikovaDepartment of Ophthalmology, Faculty of Medicine, Comenius University, (Klinika oftalmológie LFUK a UNB), Hospital Ruzinov, Ružinovská 6, 826 06, Bratislava, Slovak Republic.
Vratko HimicDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Alena FurdovaDepartment of Ophthalmology, Faculty of Medicine, Comenius University, (Klinika oftalmológie LFUK a UNB), Hospital Ruzinov, Ružinovská 6, 826 06, Bratislava, Slovak Republic. alikafurdova@gmail.com.ORCID http://orcid.org/0000-0001-5689-892X
University Hospital Bratislava · SKComenius University Bratislava · SKFakultná nemocnica s poliklinikou Žilina · SKUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this article is to evaluate the positivity of conjunctival sac swab by PCR (Polymerase chain reaction) test in COronaVIrus Disease 19 (COVID-19) patients.

methodsInclusion criteria of our study were COVID-19 patients hospitalized during March 2021 in inpatient wards at University Hospitals in towns Bratislava and Zilina, Slovakia. The conjunctival sac swabs collected by four ophthalmologists were stored for 24 h, then analyzed in the laboratory of the Department of Microbiology and Immunology, Jessenius Faculty of Medicine in Martin, Comenius University, Slovakia. The sampling apparatus, used for conjunctival sac swab, was the Dacron polyester swab.

resultsWe examined one group of 302 COVID-19 patients, 168 Male (56%) and 134 Female (44%). The patients' mean age was 66.3 ± 13.66 years, ranging from 25 to 96 years, and the mean length of hospital stay in our patients with a nasopharyngeal positive PCR test was 7.33 ± 4.76, from 2 to 24 days. The PCR tests from the conjunctival sac swabs were positive in 33 patients (11%), negative in 259 patients (86%), and ten patients (3%) were with the unclear result. In the group of 33 positive patients were 17 males with a mean age of 74.6 ± 13.59 years and 16 females with a mean age of 70.63 ± 14.17 years. The cycle threshold (C

conclusionThis study affirmed that in COVID-19 patients the SARS-CoV-2 was detectable with PCR test in conjunctival sac swab, but the positivity rate was only about one to ten cases (11%).

Indexed as

AnalysisCOVID-19Lacrimal apparatusPolymerase chain reaction

Identifiers

PMID35182227
PMCPMC8857731
OpenAlexW4213309475

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.