ReviewJournal of endocrinological investigation2022
An update on thyroid disorders in the postpartum period.
Review in Journal of endocrinological investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Do Postpartum Maternal Iodine Status or Supplementation Affect Thyroid Function After Delivery? A Systematic Review and Meta-Analysis.Biological trace element research · 2024Pooled it
- The Effect of Lactobacillus Acidophilus (La5) on the Incidence of Urinary Tract Infection in the Puerperium: A Randomized Placebo-Controlled Trial.Probiotics and antimicrobial proteins · 2026Trial
- Role of sex and gender in autoimmune thyroid diseases: mechanisms and knowledge gaps.Reviews in endocrine & metabolic disorders · 2026Review
- Review
- Postpartum Psychosis and Bipolar Disorder: Review of Neurobiology and Expert Consensus Statement on Classification.Biological psychiatry · 2026Review
- Postpartum Thyroiditis Complicated by Peripartum Cardiomyopathy and Right Ventricular Thrombi: A Case Report from Rural Uganda.International medical case reports journal · 2026Article
- The correlation between high sensitivity C-reactive protein and hypothyroidism - A cross-sectional study.Journal of family medicine and primary care · 2025Article
- The association between gestational diabetes mellitus and cancer in women: an updated systematic review and meta-analysis.Journal of diabetes and metabolic disorders · 2025Article
- Importance of iodide sufficiency and normal thyroid function in fertility and during gestation.Thyroid research · 2025Review
- Sexual Functioning and Depressive Symptoms in Women with Postpartum Thyroiditis.Diagnostics (Basel, Switzerland) · 2025Article
- Incidence of the postpartum diagnosis of thyroid eye disease in relation to thyroid function in Graves' disease.Endocrine journal · 2025Article
- Effects of postpartum hormonal changes on the immune system and their role in recovery.Acta biochimica Polonica · 2025Review
- Effect of thyroid peroxidase antibody titers trajectories during pregnancy and postpartum on postpartum thyroid dysfunction.Archives of gynecology and obstetrics · 2024Article
- Evaluation of Anti-Thyroperoxidase (A-TPO) and Anti-Thyroglobulin (A-Tg) Antibodies in Women with Previous Hashimoto's Thyroiditis during and after Pregnancy.Journal of clinical medicine · 2024Article
- Consequences of undertreatment of hypothyroidism.Endocrine · 2024Review
- Risks of suboptimal and excessive thyroid hormone replacement across ages.Journal of endocrinological investigation · 2024Review
- Diagnoses of obstetric and postpartum thyroid disease: a Danish validation study.Scientific reports · 2024Article
- Capsiate ameliorates secondary hyperparathyroidism by improving insulin sensitivity and inhibiting angiogenesis.Journal of cellular and molecular medicine · 2024Article
- Radiopharmaceuticals: A New Vista for Diagnosis and Treatment of Thyroid Cancer.Current radiopharmaceuticals · 2024Review
- Trimester-specific reference intervals for thyroid function parameters in pregnant Caucasian women using Roche platforms: a prospective study.Journal of endocrinological investigation · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo review the pathophysiology, diagnosis and management of postpartum thyroid dysfunction, and related management of thyroid disorders during lactation.
methodsWe reviewed the literature on postpartum thyroid dysfunction and management of thyroid disorders during lactation.
resultsThe postpartum period is characterized by a rebound from the immunotolerance induced by pregnancy. Routine thyroid function screening is not recommended for asymptomatic women in the postpartum period. Testing thyroid function should be considered at 6-12-week postpartum for high-risk populations, including women with a previous episode of postpartum thyroiditis, Graves' disease, or those with Hashimoto's thyroiditis on thyroid hormone replacement, known thyroid peroxidase antibody positivity, type 1 diabetes mellitus, other nonthyroidal autoimmune disease, or chronic hepatitis C. A serum TSH should also be checked in the setting of postpartum depression or difficulty lactating. If patients have thyrotoxicosis, new-onset or recurrent Graves' disease must be differentiated from postpartum thyroiditis, because the management differs. Periodic thyroid function testing is recommended following recovery from postpartum thyroiditis due to high lifetime risk of developing permanent hypothyroidism. Levothyroxine, and the lowest effective dose of antithyroid drugs, (propylthiouracil, methimazole, and carbimazole) can be safely used in lactating women. The use of radiopharmaceutical scanning is avoided during lactation and radioactive iodine treatment is contraindicated.
conclusionsDiagnosing postpartum thyroid dysfunction is challenging, because symptoms may be subtle. A team approach involving primary care providers, endocrinologists, and obstetricians is essential for transitioning thyroid care from the gestational to the postpartum setting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.