Evidence map›Paper›PMID 35181800›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2022

Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M - a case report.

Hanna Gött, Silke Kiez, Hildegard Dohmen, Malgorzata Kolodziej, Marco Stein

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Neuromodulation in Neuro-Oncology: A Scoping Review.Journal of personalized medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hanna GöttDepartment of Neurosurgery, University Hospital Giessen, Giessen, Germany. Hanna.goett@neuro.med.uni-giessen.de.
Silke KiezDepartment of Pediatric Hematooncology, University Hospital Regensburg, Regensburg, Germany.
Hildegard DohmenInstitute of Neuropathology, University Hospital Giessen, Giessen, Germany.
Malgorzata KolodziejDepartment of Neurosurgery, University Hospital Giessen, Giessen, Germany.
Marco SteinDepartment of Neurosurgery, University Hospital Giessen, Giessen, Germany.
Universitätsklinikum Gießen und Marburg · DEUniversity Hospital Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since high grade gliomas are aggressive brain tumors, intensive search for new treatment options is ongoing. For adult patients with newly diagnosed (ndGBM) and recurrent glioblastoma (rGBM), low intensity intermediate frequency alternating electric fields, known as tumor treating fields (TTFields) have been established as a new treatment modality. Tumor treating fields significantly increase survival rates in combination with adjuvant temozolomide (TMZ) in adult and GBM patients. Here, we report about feasibility and safety of treatment on a pediatric patient with diffuse midline glioma who is receiving TTFields therapy in combination with temozolomide.

Indexed as

Brain NeoplasmsElectric Stimulation TherapyGlioblastomaGliomaAdultChildChild, PreschoolCombined Modality TherapyHumansNeoplasm Recurrence, LocalTemozolomideTemozolomideDiffuse midline gliomaGlioblastomaGliomaPediatric gliomaTTFields

Identifiers

PMID35181800
PMCPMC9463302
OpenAlexW4213181491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.