ArticleMolecular psychiatry2022
Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder.
Article in Molecular psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders.Nature genetics · 2026Pooled it
- The impact of assortative mating, participation bias and socioeconomic status on the polygenic risk of behavioural and psychiatric traits.Nature human behaviour · 2024Pooled it
- Genome-wide association study in 404,302 individuals identifies 7 significant loci for reaction time variability.Molecular psychiatry · 2023Pooled it
- Unraveling the Genetic Basis of Self-Harm Phenotypes: New Perspectives on Its Links to Depression and Chronic Pain.Biological psychiatry global open science · 2026Article
- Genome-wide genetic overlap between fear-based disorders and generalised anxiety disorder.Molecular psychiatry · 2026Article
- Investigating PTSD, mental disorders, and suicide through self-comparison: a self-controlled case series study over two decades.Translational psychiatry · 2026Article
- Genome-wide association study of social isolation in 63,497 Japanese individuals from the general population.Translational psychiatry · 2026Article
- Genetic and epigenetic analysis of plasma glial fibrillary acidic protein (GFAP) levels in PTSD.Molecular psychiatry · 2026Article
- Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders.Psychiatry and clinical neurosciences · 2024Article
- Developing a phenotype risk score for tic disorders in a large, clinical biobank.Translational psychiatry · 2024Article
- Distinguishing vulnerability and resilience to posttraumatic stress disorder evaluating traumatic experiences, genetic risk and electronic health records.Psychiatry research · 2024Article
- Using Medical Records to Investigate the Genetics of Treatment-Resistant Depression Across Health Care Systems.The American journal of psychiatry · 2024Article
- Identification of Novel Genomic Loci for Anxiety and Extensive Genetic Overlap with Psychiatric Disorders.medRxiv : the preprint server for health sciences · 2024Article
- Effects of sex and gender on the etiologies and presentation of select internalizing psychopathologies.Translational psychiatry · 2024Review
- Genetic associations and potential mediators between psychiatric disorders and irritable bowel syndrome: a Mendelian randomization study with mediation analysis.Frontiers in psychiatry · 2024Article
- The role of cell adhesion molecule IgSF9b at the inhibitory synapse and psychiatric disease.Neuroscience and biobehavioral reviews · 2024Review
- A test of automated use of electronic health records to aid in diagnosis of genetic disease.Genetics in medicine : official journal of the American College of Medical Genetics · 2023Article
- Participation bias in the UK Biobank distorts genetic associations and downstream analyses.Nature human behaviour · 2023Article
- Functional and molecular characterization of suicidality factors using phenotypic and genome-wide data.Molecular psychiatry · 2023Article
- Sex-Specific Genetic and Transcriptomic Liability to Neuroticism.Biological psychiatry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 6 institutions in 1 country.
Funding
Abstract
UK Biobank (UKB) is a key contributor in mental health genome-wide association studies (GWAS) but only ~31% of participants completed the Mental Health Questionnaire ("MHQ responders"). We predicted generalized anxiety disorder (GAD), posttraumatic stress disorder (PTSD), and major depression symptoms using elastic net regression in the ~69% of UKB participants lacking MHQ data ("MHQ non-responders"; N
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.