ArticleScientific reports2022
Association between depression and anxiety on symptom and function after surgery for lumbar spinal stenosis.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Implications of Preoperative Depression for Lumbar Spine Surgery Outcomes: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Basivertebral nerve ablation provides comparable early pain relief in patients with psychiatric conditions: A real-world study.Interventional pain medicine · 2026Article
- The application of local lesion postoperative continuous irrigation for the perioperative management of spinal tuberculosis with posterior-only approach surgery.Scientific reports · 2025Article
- Letter to the editor concerning "Anxiety and depression 1-year after spinal tumor surgery: a retrospective analysis of psychological and clinical predictors" by R.Z. Ahmed, et al. (Eur spine J [2025]; doi: 10.1007/s00586-025-09325-7).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Valuable Prognostic Role of Disability, Pain, Anxiety, and Depression Scales in Instrumented Lumbar Spine Surgery for Degenerative Pathology: The SAP-LD Study.Brain sciences · 2025Article
- Analysis of preoperative and postoperative depression and anxiety in patients with calcaneal fractures.BMC psychiatry · 2025Article
- Preoperative psychological health impacts pain and disability outcomes following anterior cervical discectomy and fusion for cervical radiculopathy.Scientific reports · 2025Article
- Increase in (semi-) acute non-instrumented lumbar spine surgeries during the COVID-19 pandemic.Brain & spine · 2025Article
- Artificial neural network analysis of factors affecting functional independence recovery in patients with lumbar stenosis after neurosurgery treatment: An observational cohort study.Journal of orthopaedics · 2024Article
- Prospective Study of the Assessment of Anxiety Symptoms after Minimally Invasive Lumbar Decompression.Revista brasileira de ortopedia · 2024Article
- Impact of Depression on Postoperative Medical and Surgical Outcomes in Spine Surgeries: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Article
- The role of psychopathological symptoms in lumbar stenosis: A prediction model of disability after lumbar decompression and fusion.Frontiers in psychology · 2023Article
- Predictors of residual low back pain in patients with osteoporotic vertebral fractures following percutaneous kyphoplasty.Frontiers in surgery · 2023Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence on the role of depression and anxiety in patients undergoing surgical treatment for symptomatic degenerative lumbar spinal stenosis (DLSS) is conflicting. We aimed to assess the association between depression and anxiety with symptoms and function in patients undergoing surgery for DLSS. Included were patients with symptomatic DLSS participating in a prospective multicentre cohort study who underwent surgery and completed the 24-month follow-up. We used the hospital anxiety and depression scale (HADS) to assess depression/anxiety. We used mixed-effects models to quantify the impact on the primary outcome change in the spinal stenosis measure (SSM) symptoms/function subscale from baseline to 12- and 24-months. Logistic regression analysis was used to quantify the odds of the SSM to reach a minimal clinically important difference (MCID) at 24 months follow-up. The robustness of the results in the presence of unmeasured confounding was quantified using a benchmarking method based on a multiple linear model. Out of 401 patients 72 (17.95%) were depressed and 80 anxious (19.05%). Depression was associated with more symptoms (β = 0.36, 95% confidence interval (CI) 0.20 to 0.51, p < 0.001) and worse function (β = 0.37, 95% CI 0.24 to 0.50, p < 0.001) at 12- and 24-months. Only the association between baseline depression and SSM symptoms/function was robust at 12 and 24 months. There was no evidence for baseline depression/anxiety decreasing odds for a MCID in SSM symptoms and function over time. In patients undergoing surgery for symptomatic DLSS, preoperative depression but not anxiety was associated with more severe symptoms and disability at 12 and 24 months.
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