Evidence map›Paper›PMID 35181691›Full record

ArticleScientific reports2022

Afidopyropen, a novel insecticide originating from microbial secondary extracts.

Ryo Horikoshi, Kimihiko Goto, Masaaki Mitomi, Kazuhiko Oyama, Tomoyasu Hirose, Toshiaki Sunazuka, Satoshi Ōmura

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
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  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. A Timeline of Biosynthetic Gene Cluster Discovery inJournal of fungi (Basel, Switzerland) · 2024
    Article
  11. Article
  12. Two detoxification enzyme genes,Frontiers in physiology · 2024
    Article
  13. Anti-Insect Properties ofMicroorganisms · 2023
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ryo HorikoshiAgricultural and Veterinary Research Labs., Agricultural and Veterinary Division, Meiji Seika Pharma Co., Ltd., 760 Morooka-cho, Kohoku-ku, Yokohama, 222-8567, Japan. Ryou.Horikoshi@mitsuichemicals.com.
Kimihiko GotoAgricultural and Veterinary Research Labs., Agricultural and Veterinary Division, Meiji Seika Pharma Co., Ltd., 760 Morooka-cho, Kohoku-ku, Yokohama, 222-8567, Japan.
Masaaki MitomiAgricultural and Veterinary Research Labs., Agricultural and Veterinary Division, Meiji Seika Pharma Co., Ltd., 760 Morooka-cho, Kohoku-ku, Yokohama, 222-8567, Japan.
Kazuhiko OyamaAgricultural and Veterinary Research Labs., Agricultural and Veterinary Division, Meiji Seika Pharma Co., Ltd., 760 Morooka-cho, Kohoku-ku, Yokohama, 222-8567, Japan.
Tomoyasu HiroseGraduate School of Infection Control Sciences, Ōmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.
Toshiaki SunazukaGraduate School of Infection Control Sciences, Ōmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.
Satoshi ŌmuraGraduate School of Infection Control Sciences, Ōmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.
Unitika (Japan) · JPKitasato University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Afidopyropen, a novel insecticide, is a derivative of pyripyropene A, which is produced by the filamentous fungus Penicillium coprobium. Afidopyropen has strong insecticidal activity against aphids and is currently used as a control agent of sucking pests worldwide. In this study, we summarized the biological properties and field efficacies of its derivatives against agricultural pests using official field trials conducted in Japan. Afidopyropen showed good residual efficacies against a variety of aphids, whiteflies and other sucking pests under field conditions. Furthermore, toxicological studies revealed its safety profiles against nontarget organisms, such as the honeybee, natural enemies and other beneficial insects, as well as mammals. Thus, afidopyropen is a next-generation agrochemical for crop protection that has a low environmental impact.

Indexed as

AnimalsAphidsHeterocyclic Compounds, 4 or More RingsInsecticidesJapanLactonesPenicilliumPyridinesSesquiterpenesafidopyropenHeterocyclic Compounds, 4 or More RingsInsecticidesLactonesPyridinespyripyropene ASesquiterpenes

Identifiers

PMID35181691
PMCPMC8857236
OpenAlexW4213341662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.