Evidence map›Paper›PMID 35181597›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

Time Course of Activity-Dependent Changes in Auditory Nerve Synapses Reveals Multiple Underlying Cellular Mechanisms.

Nicole F Wong, Matthew A Xu-Friedman

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Convergence of Type 1 Spiral Ganglion Neuron Subtypes onto Principal Neurons of the Anteroventral Cochlear Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Article
  6. Article
  7. Induction of Activity-Dependent Plasticity at Auditory Nerve Synapses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicole F WongDepartment of Biological Sciences, University at Buffalo, State University of New York, Buffalo, New York 14260.
Matthew A Xu-FriedmanDepartment of Biological Sciences, University at Buffalo, State University of New York, Buffalo, New York 14260 mx@buffalo.edu.
University at Buffalo, State University of New York · US

Funding

Activity-dependent regulation of auditory nerve synapses in the cochlear nucleusR01DC015508 · NIDCD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI XU-FRIEDMAN, MATTHEW A. · 2017 to 2021
$1.7M
NIDCD NIH HHS R01 DC015508
6 · The paper itself

Abstract

Abnormal levels of acoustic activity can result in hearing problems such as tinnitus and language processing disorders, but the underlying cellular and synaptic changes triggered by abnormal activity are not well understood. To address this issue, we studied the time course of activity-dependent changes that occur at auditory nerve synapses in mice of both sexes after noise exposure and conductive hearing loss. We found that EPSC amplitude and synaptic depression decreased within 2 d of noise exposure through a decrease in the probability of vesicle release (

Indexed as

Cochlear NerveHearing Loss, ConductiveAnimalsAuditory PathwaysFemaleMaleMiceNoiseSynapsesactivity-dependent changesauditory nervecochlear nucleusendbulb of Heldsynaptic plasticity

Identifiers

PMID35181597
PMCPMC8944231
OpenAlexW4213070909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.