Evidence map›Paper›PMID 35181177›Full record

ArticlePatient education and counseling2022

Examining the direct and indirect effects of trust in motivating COVID-19 vaccine uptake.

Sixiao Liu, Haoran Chu

Abstract read
In one paragraph

Article in Patient education and counseling, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  11. Building Parental Trust in Childhood Vaccination: Lessons From Iran's COVID-19 Response.International journal of health policy and management · 2025
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  18. U.S. adults' reasons for changing their degree of willingness to vaccinate against COVID-19.Zeitschrift fur Gesundheitswissenschaften = Journal of public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sixiao LiuAnnenberg School for Communication, University of Pennsylvania, Philadelphia, USA. Electronic address: vivian.liu@asc.upenn.edu.
Haoran ChuDepartment of Public Relations, University of Florida, Gainesville, USA. Electronic address: chu.h@ufl.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to investigate how trust in healthcare providers, public health agencies, politicians, and pharmaceutical companies shaped people's attitudes and behavioral intention associated with COVID-19 vaccination, directly and indirectly via the mediation of vaccine evaluation and emotions.

methodsA two-wave longitudinal survey (N = 534) was employed in late 2020 and early 2021 to assess the direct and indirect relationships between trust on people's attitude toward the COVID-19 vaccine, vaccination intention, and actual vaccine uptake.

resultsResults show that trust was positively associated with attitude toward the COVID-19 vaccines and vaccination intention, both directly and indirectly via the mediation of vaccine evaluation, hope, and anger. Vaccination intention also mediated trust's influence on vaccine uptake.

conclusionTrust in health providers, vaccine manufacturers, and public health agencies are vital to public acceptance of the COVID-19 vaccine. PRACTICE IMPLICATIONS: Healthcare providers and vaccine manufacturers may serve as the most effective source to communicate COVID-19 vaccine-related information. Trusted health communicators need to highlight the effectiveness and safety of the vaccine while maintaining a positive tone.

Indexed as

COVID-19Influenza VaccinesCOVID-19 VaccinesHumansIntentionTrustVaccinationCOVID-19 VaccinesInfluenza VaccinesCOVID-19 vaccineEmotionTrustVaccine uptake

Identifiers

PMID35181177
PMCPMC8840822

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.