Evidence map›Paper›PMID 35180534›Full record

ReviewCurrent opinion in virology2022

Phage banks as potential tools to rapidly and cost-effectively manage antimicrobial resistance in the developing world.

Tobi Nagel, Lillian Musila, Milkah Muthoni, Mikeljon Nikolich, Jesca L Nakavuma, Martha Rj Clokie

Abstract readReview
In one paragraph

Review in Current opinion in virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Characterization ofMicrobiology spectrum · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Rolling outMicrobial genomics · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Isolation and characterization of a lytic phage and its efficacy against multi-drug resistant strains of pseudomonas aeruginosa.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  16. Article
  17. Eliminating the type I restriction endonuclease fromMicrobiology (Reading, England) · 2025
    Article
  18. The future of phage therapy in the USA.Trends in molecular medicine · 2025
    Review
  19. Article
  20. Bacteria-phage infection network structure and genomic defence system content predict efficacy of a phage therapy cocktail againstPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tobi NagelPhages for Global Health, 383 62nd Street, Oakland, CA 94618, USA. Electronic address: tobi@phagesforglobalhealth.org.
Lillian MusilaU.S. Army Medical Research Directorate-Africa, P.O. Box 606-00621, Nairobi, Kenya.
Milkah MuthoniKenya Medical Research Institute, P.O. Box 54840-00200, Nairobi, Kenya.
Mikeljon NikolichWound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA.
Jesca L NakavumaSchool of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Martha Rj ClokieDepartment of Genetics and Genome Biology, University of Leicester, University Road, LE1 7RH, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lower and middle-income countries seldom develop vaccines and therapeutics for their own populations and are dependent on supplies from industrialized countries, which are often hampered by financial or supply chain limitations. This has resulted in major delays in delivery with significant loss of life, as seen with the coronavirus pandemic. Since the vast majority of deaths from the antimicrobial resistance crisis are expected to occur in developing countries, there is an urgent need for in-country production of antibacterial therapies such as phages. Nationally controlled phage banks might provide such a solution since locally developed phage therapies tailored to endemic bacterial strains could offer cost-effective antibiotic alternatives.

Indexed as

BacteriophagesPhage TherapyAnti-Bacterial AgentsBacteriaDrug Resistance, BacterialAnti-Bacterial Agents

Identifiers

PMID35180534
PMCPMC8846552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.