ArticleClinical nutrition (Edinburgh, Scotland)2022
Validity of four commercially available metabolic carts for assessing resting metabolic rate and respiratory exchange ratio in non-ventilated humans.
Article in Clinical nutrition (Edinburgh, Scotland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07462806 (Indirect Calorimetry Measurement in the Paediatric Intensive Care Unit's Smallest Patients), which is not on this map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Indirect Calorimetry Measurement in the Paediatric Intensive Care Unit's Smallest Patients
Who cites it
20 citing papers in PubMed.
- Trial
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- Daily validation using a metabolic simulator after regular calibration increases the quality of cardiopulmonary exercise testing.Journal of thoracic disease · 2025Article
- Using Respiratory Gas Analyzers to Determine Resting Metabolic Rate in Adults: A Systematic Review of Validity Studies.Sports (Basel, Switzerland) · 2025Review
- Integrative Field-Based Health and Performance Research: A Narrative Review on Experimental Methods and Logistics to Conduct Competition and Training Camp Studies in Athletes.Sports medicine (Auckland, N.Z.) · 2025Review
- Proposed shorter duration protocols for measuring resting energy expenditure utilizing whole-room indirect calorimetry.International journal of obesity (2005) · 2025Article
- Article
- Cardiorespiratory demands of firearms training instruction and 15m shuttle tests in British law enforcement.PloS one · 2025Article
- Predicting Steady-State Metabolic Power in Cerebral Palsy, Stroke, and the Elderly During Walking With and Without Assistive Devices.Annals of biomedical engineering · 2025Article
- ENERGY expenditure of COmmuting to school (ENERGYCO): protocol for a cluster randomized controlled trial.Frontiers in public health · 2025Article
- Whole-body volume of oxygen consumption while walking: Agreement between measured and estimated values.European journal of sport science · 2024Article
- Association of metabolic flexibility indexes after an oral glucose tolerance test with cardiometabolic risk factors.European journal of clinical nutrition · 2024Article
- Resting energy metabolism and sweet taste preference during the menstrual cycle in healthy women.The British journal of nutrition · 2024Article
- Predicting resting energy expenditure: a critical appraisal.European journal of clinical nutrition · 2023Article
- Resting Metabolic Rate of Individuals.Metabolites · 2023Article
- Associations between Intra-Assessment Resting Metabolic Rate Variability and Health-Related Factors.Metabolites · 2022Article
- Acute Effects of Whole-Body Electromyostimulation on Energy Expenditure at Resting and during Uphill Walking in Healthy Young Men.Metabolites · 2022Article
- The cost of chewing: The energetics and evolutionary significance of mastication in humans.Science advances · 2022Article
- A nutritional intervention for moderate altitude endurance preparation: A case report.Journal of the International Society of Sports Nutrition · 2022Article
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Authors and funding
8 authors.
Funding
Abstract
BACKGROUND &
aimsThe validity of most commercially available metabolic cart is mostly unknown. Thus, we aimed to determine the accuracy, precision, within-subject reproducibility, and concordance of RMR and RER measured by four commercially available metabolic carts [Cosmed Q-NRG, Vyaire Vyntus CPX, Maastricht Instruments Omnical, and Medgraphics Ultima CardiO2]. Further, we studied whether a previously proposed simulation-based post-calorimetric calibration of cart readouts [individual calibration control evaluation (ICcE)] modify the RMR and RER reproducibility and concordance.
methodsThree experiments simulating different RMR and RER by controlled pure gas (N
resultsThe Omnical presented the lowest measurement error for RER (Omnical = 1.7 ± 0.9%; Vyntus = 4.5 ± 2.0%; Q-NRG = 6.6 ± 1.9%; Ultima = 6.8 ± 6.5%) and EE (Omnical = 1.5 ± 0.5%; Q-NRG = 2.5 ± 1.3%; Ultima = 10.7 ± 11.0%; Vyntus = 13.8 ± 5.0%) in all in vitro experiments (controlled pure gas infusions and methanol burns). In humans, the 4 metabolic carts provided discordant RMR and RER estimations (all P < 0.001). No differences were detected in RMR within-subject reproducibility (P = 0.058; Q-NRG inter-day coefficient of variance = 3.6 ± 2.5%; Omnical = 4.8 ± 3.5%; Vyntus = 5.0 ± 5.6%; Ultima = 5.7 ± 4.6%), although the Ultima CardiO2 provided larger RER inter-day differences (4.6 ± 3.5%) than the others carts (P = 0.001; Omnical = 1.9 ± 1.7%; Vyntus = 2.1 ± 1.3%; Q-NRG = 2.4 ± 2.1%). The ICcE procedure did not modify the RMR or RER concordance and did not reduce the inter-day differences in any of the carts.
conclusionsThe 4 metabolic carts provided discordant measurements of RMR and RER. Overall, the Omnical provides more accurate and precise estimations of RMR and RER than the Q-NRG, Vyntus and Ultima CardiO2, and might be considered the best for assessing RMR and RER in non-ventilated humans. Finally, our results do not support the use of an ICcE procedure.
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