Evidence map›Paper›PMID 35180431›Full record

ArticleCell chemical biology2022

No acetyl-CoA keeps Plasmodium at bay.

Victoria Jeffers, Matthew A Child

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Victoria JeffersDepartment of Molecular, Cellular and Biomedical Life Sciences, University of New Hampshire, Durham NH 03824, USA. Electronic address: victoria.jeffers@unh.edu.
Matthew A ChildDepartment of Life Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, UK. Electronic address: m.child@imperial.ac.uk.
Imperial College London · GBUniversity of New Hampshire · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acetyl-coenzyme A is an important metabolite and regulates diverse cellular processes, including metabolism and epigenetics. In this issue of Cell Chemical Biology, Summers et al. (2022) describe an essential parasite enzyme, acetyl-coenzyme A synthetase, as a target of two antimalarial small molecules active against liver and blood stages of the parasite.

Indexed as

AntimalarialsParasitesPlasmodiumAcetyl Coenzyme AAnimalsPlasmodium falciparumAcetyl Coenzyme AAntimalarials

Identifiers

PMID35180431
OpenAlexW4212792372

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.