SynthesisAmerican journal of respiratory and critical care medicine2022
Association of Positive End-Expiratory Pressure and Lung Recruitment Selection Strategies with Mortality in Acute Respiratory Distress Syndrome: A Systematic Review and Network Meta-analysis.
Registry-linked trialOpen access · greenAbstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph
Synthesis in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07673250 (Personalized Ventilator Settings for Patients on ECMO), which is not on this map. Cited by 58 papers, 6 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 6 pooled it
16.1field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Personalized Ventilator Settings for Patients on ECMO (PEEPECMO)
Who cites it
58 citing papers in PubMed, 6 syntheses or guidelines pooled it, 113 citations in OpenAlex.
- Clinical Practice Guideline: Mechanical Ventilation and Extracorporeal Membrane Oxygenation in Acute Respiratory Insufficiency.Deutsches Arzteblatt international · 2026Guideline
- [S3 guideline on sepsis-prevention, diagnosis, therapy, and follow-up care-update 2025].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Guideline
- AARC Clinical Practice Guideline: Patient-Ventilator Assessment.Respiratory care · 2024Guideline
- Effectiveness of Fludrocortisone Plus Hydrocortisone versus Hydrocortisone Alone in Septic Shock: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.American journal of respiratory and critical care medicine · 2024Pooled it
- An Update on Management of Adult Patients with Acute Respiratory Distress Syndrome: An Official American Thoracic Society Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2024Guideline
- Mechanical ventilation in patients with acute brain injury: a systematic review with meta-analysis.Critical care (London, England) · 2023Pooled it
- Transpulmonary Pressure as a Predictor of Successful Lung Recruitment: Reanalysis of a Multicenter International Randomized Clinical Trial.Respiratory care · 2025Trial
- Electric impedance tomography-guided PEEP titration reduces mechanical power in ARDS: a randomized crossover pilot trial.Critical care (London, England) · 2023Trial
- Association Between Cdyn-Guided PEEP and Nursing Activities During PACU Recovery in Infants Undergoing One-Lung Ventilation: A Retrospective Observational Cohort Study.Nursing open · 2026Observational
- Balancing lung and brain: physiological strategies for ARDS management in acute brain injury.Intensive care medicine · 2026Review
- A Biofabricated Human Acinus-on-a-Chip Unveils Mechanotransductive Drivers of Ventilator-Induced Lung Injury via Decoupling Volutrauma and Barotrauma.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Early career member highlights from the ERS Respiratory Failure and Mechanical Ventilation Conference 2026.Breathe (Sheffield, England) · 2026Article
- Clamping of the endotracheal tube to preserve the level of PEEP during disconnection from the ventilation circuit - a survey on routine practice.BMC anesthesiology · 2026Article
- Positive end-expiratory pressure in pediatric acute respiratory distress syndrome: a narrative review.Translational pediatrics · 2026Review
- Mechanical ventilation in ARDS: navigating the fine line with real-time monitoring.Critical care (London, England) · 2026Review
- Management of Mechanical Ventilation in Emergency Medicine: A Scoping Review.Journal of the American College of Emergency Physicians open · 2026Review
- Article
- Toward optimal mechanical ventilation of the injured lung: the role of expiratory duration.Critical care (London, England) · 2025Review
- [Ten key messages of the German S3 guideline on invasive ventilation and use of extracorporeal techniques in patients with acute respiratory failure].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Review
- Optimizing Positive End-Expiratory Pressure in Asymmetric Acute Lung Injury in a Porcine Model: The Role of Transpulmonary Pressure.International journal of molecular sciences · 2025Article
Corrections and comments
- Commented on by
Authors and funding
22 authors at 12 institutions in 6 countries.
Jose DiantiUniversity Health Network/Sinai Health System.ORCID 0000-0003-2016-7003
Manuel TisminetzkyUniversity Health Network/Sinai Health System.ORCID 0000-0002-8917-5266
Bruno L FerreyroUniversity Health Network/Sinai Health System.
Marina EnglesakisLibrary and Information Services, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0002-2199-1056
Lorenzo Del SorboUniversity Health Network/Sinai Health System.ORCID 0000-0003-3294-9838
Sachin SudInstitute for Better Health and Critical Care, Department of Medicine, Trillium Health Partners, Mississauga, Ontario, Canada.ORCID 0000-0002-9602-6509
Daniel TalmorDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Lorenzo BallDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.
Maureen MeadeDivision of Critical Care, Department of Medicine.
Carol HodgsonAustralian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia.ORCID 0000-0001-9002-2075
Jeremy R BeitlerCenter for Acute Respiratory Failure and Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons and New York-Presbyterian Hospital, New York, New York.ORCID 0000-0003-0797-2374
Sarina SahetyaDivision of Pulmonary and Critical Care, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.ORCID 0000-0003-2127-3609
Alistair NicholAustralian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia.
Eddy FanUniversity Health Network/Sinai Health System.
Bram RochwergDivision of Critical Care, Department of Medicine.ORCID 0000-0002-8293-7061
Laurent BrochardInterdepartmental Division of Critical Care Medicine.
Arthur S SlutskyInterdepartmental Division of Critical Care Medicine.
Niall D FergusonUniversity Health Network/Sinai Health System.
Ary Serpa NetoDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Neill K J AdhikariInterdepartmental Division of Critical Care Medicine.ORCID 0000-0003-4038-5382
Federico AngrimanInterdepartmental Division of Critical Care Medicine.ORCID 0000-0003-0971-386X
Ewan C GoligherUniversity Health Network/Sinai Health System.ORCID 0000-0002-0990-6701
University Health Network · CAImpact · CASt. Michael's Hospital · CASunnybrook Health Science Centre · CAAlfred Health · AUBeth Israel Deaconess Medical Center · USJohns Hopkins University · USNewYork–Presbyterian Hospital · USThe University of Melbourne · AUTrillium Health Centre · CAUniversity College Dublin · IEUniversity of Genoa · IT
Funding
Driving Pressure as a Target for Lung-Protective VentilationK23HL155507 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SAHETYA, SARINA · 2021 to 2025
$885kBreath stacking dyssynchrony in acute respiratory distress syndromeK23HL133489 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BEITLER, JEREMY R. · 2017 to 2021
$871kMeasuring lung stress to identify occult ventilation-induced lung injury in ARDSR21HL145506 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BEITLER, JEREMY R. · 2019 to 2020
$243kCIHRNHLBI NIH HHS K23 HL133489NHLBI NIH HHS K23 HL155507NHLBI NIH HHS R21 HL145506
Abstract
PubMed holds no abstract for this paper.
Indexed as
Positive-Pressure RespirationRespiratory Distress SyndromeAdultBayes TheoremHumansLungARDShypoxemic respiratory failurelung recruitment maneuvermortalityPEEP
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT07673250ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.