ArticleAdvanced materials (Deerfield Beach, Fla.)2022
Open-Shell Nanosensitizers for Glutathione Responsive Cancer Sonodynamic Therapy.
Open access · bronzeAbstract read
In one paragraph
Article in Advanced materials (Deerfield Beach, Fla.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.
- Collagenase-mediated extracellular matrix targeting for enhanced drug penetration and therapeutic efficacy in nanoscale delivery systems for cancer therapy.Journal of nanobiotechnology · 2025Pooled it
- CPT-TCPP polymeric nanoplatform for sonodynamic-chemotherapy synergistic tumor therapy through ferroptosis-apoptosis dual cell death reprogramming.Materials today. Bio · 2026Article
- Nanobiotechnology-driven advances in sonodynamic therapy: unlocking the potential of sonosensitizers in clinical translation.RSC advances · 2026Review
- Transformable Tumor Microenvironment-Responsive Oxygen Vacancy-Rich MnOAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Multi-component Microcapsules Derived Spatiotemporal Sonodynamic Reinforcing Therapy against Rheumatoid Arthritis.Research (Washington, D.C.) · 2025Article
- Nanocatalytic medicine enabled next-generation therapeutics for bacterial infections.Materials today. Bio · 2024Review
- Precise Clearance of Intracellular MRSA via Internally and Externally Mediated Bioorthogonal Activation of Micro/Nano Hydrogel Microspheres.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Application and Challenge of Metalloporphyrin Sensitizers in Noninvasive Dynamic Tumor Therapy.Molecules (Basel, Switzerland) · 2024Review
- Nanorepair medicine for treatment of organ injury.National science review · 2024Review
- Oxygen-carrying semiconducting polymer nanoprodrugs induce sono-pyroptosis for deep-tissue tumor treatment.Exploration (Beijing, China) · 2024Article
- Selenium-Doped Nanoheterojunctions for Highly Efficient Cancer Radiosensitization.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Novel Spatially Asymmetric Copper Bismuthate-Mediated Augmentation of Energy Conversion to Realize "Three-Step" Tumor Suppression.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Advances in Nanodynamic Therapy for Cancer Treatment.Nanomaterials (Basel, Switzerland) · 2024Review
- Nanomaterials-Induced Redox Imbalance: Challenged and Opportunities for Nanomaterials in Cancer Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- What Is the Magical Cavitation Bubble: A Holistic Perspective to Trigger Advanced Bubbles, Nano-Sonocatalysts, and Cellular Sonosensitizers.BME frontiers · 2024Review
- Engineering Heterogeneous Tumor Models for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- GSH-activated Porphyrin Sonosensitizer Prodrug for Fluorescence Imaging-guided Cancer Sonodynamic Therapy.Advanced functional materials · 2023Article
- 2D Nano-Sonosensitizers Facilitate Energy Transfer to Enhance Sonodynamic Therapy.Advanced materials (Deerfield Beach, Fla.) · 2023Article
- Biomimetic Gland Models with Engineered Stratagems.Research (Washington, D.C.) · 2023Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 2 countries.
Han WangDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P. R. China.
Jinxiao GuoDepartment of Orthopaedics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200233, P. R. China.
Wilson LinDepartments of Radiology and Medical Physics, University of Wisconsin, Madison, WI, 53705, USA.
Zi FuDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P. R. China.
Xiuru JiDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P. R. China.
Bo YuDepartments of Radiology and Medical Physics, University of Wisconsin, Madison, WI, 53705, USA.
Min LuDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P. R. China.
Wenguo CuiDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P. R. China.
Lianfu DengDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P. R. China.
Jonathan W EngleDepartments of Radiology and Medical Physics, University of Wisconsin, Madison, WI, 53705, USA.
Zhiyuan WuDepartment of Interventional Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P. R. China.
Weibo CaiDepartments of Radiology and Medical Physics, University of Wisconsin, Madison, WI, 53705, USA.ORCID https://orcid.org/0000-0003-4641-0833
Dalong NiDepartment of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P. R. China.
Shanghai Jiao Tong University · CNUniversity of Wisconsin–Madison · US
Funding
UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6MNanogenerator-Driven Self-Sustainable Power Source for Intracardiac PacemakersR01HL157077 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI WANG, XUDONG · 2021 to 2024
$2.7MUltrasound-Activated Piezoelectric P(VDF-TrFE) Nanoparticles for Electric Ablation of Cancer CellsR21EB027857 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI CAI, WEIBO, WANG, XUDONG · 2019 to 2020
$413kNCI NIH HHS P30 CA014520NHLBI NIH HHS R01 HL157077NIBIB NIH HHS R21 EB027857NIH HHS P30CA014520
Abstract
Deleterious effects to normal tissues and short biological half-life of sonosensitizers limit the applications of sonodynamic therapy (SDT). Herein, a new sonosensitizer (Cu(II)NS) is synthesized that consists of porphyrins, chelated Cu
Indexed as
NeoplasmsPorphyrinsUltrasonic TherapyCell Line, TumorGlutathioneHumansPolyethylene GlycolsGlutathionePolyethylene GlycolsPorphyrinsglutathione responsenanomedicineopen shellpositron emission tomography imagingsonodynamic therapy
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.