ArticlePlant biotechnology journal2022
Identification of ST1 reveals a selection involving hitchhiking of seed morphology and oil content during soybean domestication.
Article in Plant biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 69 citations in OpenAlex.
- Korean Soybean Nested Association Mapping (K-SoyNAM) population: genetic linkage map, genetic mapping, and genotype imputation.BMC genomics · 2026Article
- An underutilized genetic component in the regulation of soybean seed weight.Nature communications · 2026Article
- QTL/Segment Mapping and Candidate Gene Analysis for Oil Content Using a Wild Soybean Chromosome Segment Substitution Line Population.Plants (Basel, Switzerland) · 2026Article
- Identification of QTL associated with pod number in soybean.Frontiers in genetics · 2026Article
- Genome-wide detection of superior haplotypes for seed oil and protein content in Northeast China soybean (Frontiers in plant science · 2026Article
- Transcriptome and Metabolome Analyses Reveal the Accumulation Mechanism of Carbohydrates DuringBiomolecules · 2025Article
- A 14-3-3 modulator of seed weight and quality for unlocking the yield potential of soybean.Nature communications · 2025Article
- Loci and natural alleles for leaf length and width revealed by a genome wide association study in adzuki bean.BMC plant biology · 2025Article
- A natural allele ofProceedings of the National Academy of Sciences of the United States of America · 2025Article
- GmSop20 Functions as a Key Coordinator of the Oil-To-Protein Ratio in Soybean Seeds.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- GmCDC7 is involved in coordinating seed size and quality in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Natural allelic variation in SW14 determines seed weight and quality in soybean.Nature communications · 2025Article
- Image-based GWAS identifies the genetic architecture of seed-related traits in a soybean mutant population.Molecular breeding : new strategies in plant improvement · 2025Article
- Knockout ofPlants (Basel, Switzerland) · 2025Article
- Conditional QTL/QTN mapping for seed width and mining candidate genes based on soybean FW-RIL population.Molecular genetics and genomics : MGG · 2025Article
- Loss of phytochromobilin synthase activity leads to larger seeds with higher protein content in soybean.BMC plant biology · 2025Article
- Identification of superior haplotypes and candidate gene for seed size-related traits in soybean (Molecular breeding : new strategies in plant improvement · 2025Article
- Comparative transcriptome analysis of vegetable soybean grain discloses genes essential for grain quality.BMC plant biology · 2024Article
- Integrative omics analysis elucidates the genetic basis underlying seed weight and oil content in soybean.The Plant cell · 2024Article
- Integrated Transcriptomic and Proteomic Characterization of a Chromosome Segment Substitution Line Reveals the Regulatory Mechanism Controlling the Seed Weight in Soybean.Plants (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seed morphology and quality of cultivated soybean (Glycine max) have changed dramatically during domestication from their wild relatives, but their relationship to selection is poorly understood. Here, we describe a semi-dominant locus, ST1 (Seed Thickness 1), affecting seed thickness and encoding a UDP-D-glucuronate 4-epimerase, which catalyses UDP-galacturonic acid production and promotes pectin biosynthesis. Interestingly, this morphological change concurrently boosted seed oil content, which, along with up-regulation of glycolysis biosynthesis modulated by ST1, enabled soybean to become a staple oil crop. Strikingly, ST1 and an inversion controlling seed coat colour formed part of a single selective sweep. Structural variation analysis of the region surrounding ST1 shows that the critical mutation in ST1 existed in earlier wild relatives of soybean and the region containing ST1 subsequently underwent an inversion, which was followed by successive selection for both traits through hitchhiking during selection for seed coat colour. Together, these results provide direct evidence that simultaneously variation for seed morphology and quality occurred earlier than variation for seed coat colour during soybean domestication. The identification of ST1 thus sheds light on a crucial phase of human empirical selection in soybeans and provides evidence that our ancestors improved soybean based on taste.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.