Evidence map›Paper›PMID 35178413›Full record

ArticleFrontiers in medicine2022

Immigrant IBD Patients in Spain Are Younger, Have More Extraintestinal Manifestations and Use More Biologics Than Native Patients.

Ana Gutiérrez, Pedro Zapater, Elena Ricart, María González-Vivó, Jordi Gordillo, David Olivares, Isabel Vera, Míriam Mañosa, Javier P Gisbert, Mariam Aguas and 56 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

66 authors at 20 institutions in 1 country.

Ana GutiérrezServicio Medicina Digestiva, Hospital General Universitario Alicante, Alicante, Spain.
Pedro ZapaterIIS Isabial, Hospital General Universitario Alicante, Alicante, Spain.
Elena RicartCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
María González-VivóServicio Medicina Digestiva, Hospital del Mar, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
Jordi GordilloServicio Patología Digestiva, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain.
David OlivaresServicio Medicina Digestiva, Hospital Universitario Clínico San Carlos, Madrid, Spain.
Isabel VeraServicio Aparato Digestivo, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Míriam MañosaCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
Javier P GisbertCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
Mariam AguasCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
Eugenia Sánchez-RodríguezServicio Medicina Digestiva, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Maia Bosca-WattsServicio Medicina Digestiva, Hospital Clínico Universitario de Valencia, Valencia, Spain.
Viviana LaredoServicio Medicina Digestiva, Hospital Clinico Universitario Lozano Blesa, Zaragoza, Spain.
Blau CampsServicio Medicina Digestiva, Hospital Universitario de Bellvitge, Barcelona, Spain.
Ignacio Marín-JiménezServicio Medicina Digestiva, Hospital Gregorio Marañón, Madrid, Spain.
Yamile ZabanaCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
María Dolores Martín-ArranzServicio Medicina Digestiva, Hospital La Paz, Madrid, Spain.
Roser MuñozServicio Medicina Digestiva, Hospital General Universitario Alicante, Alicante, Spain.
Mercè NavarroServicio Medicina Digestiva, Hospital de Sant Joan Despí Moisès Broggi, Barcelona, Spain.
Eva SierraServicio Medicina Digestiva, Hospital Universitario Miguel Servert, Zaragoza, Spain.
Lucía MaderoServicio Medicina Digestiva, Hospital General Universitario de Elche, Elche, Spain.
Milagros VelaServicio Medicina Digestiva, Hospital Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain.
José Lázaro Pérez-CalleServicio Medicina Digestiva, Hospital Universitario Fundación de Alcorcón, Madrid, Spain.
Empar SainzServicio Medicina Digestiva, Hospital Sant Joan de Déu - Althaia, Manresa, Spain.
Xavier CalvetCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
Lara AriasServicio Medicina Digestiva, Hospital Universitario de Burgos, Burgos, Spain.
Victor MoralesServicio Medicina Digestiva, Hospital General de Granollers, Barcelona, Spain.
Fernando BermejoServicio Medicina Digestiva, Hospital de Fuenlabrada, Fuenlabrada, Spain.
Luis Fernández-SalazarServicio Medicina Digestiva, Hospital Clínico de Valladolid, Madrid, Spain.
Manuel Van DomselaarServicio Medicina Digestiva, Hospital de Torrejón de Ardoz, Madrid, Spain.
Luisa De CastroDepartment of Gastroenterology, Xerencia Xestion Integrada de Vigo- SERGAS. IIS Galicia Sur. SERGAS-UVIG, Vigo, Spain.
Cristina RodríguezServicio Medicina Digestiva, Complejo Hospitalario de Navarra, Pamplona, Spain.
Carmen Muñoz-VillafrancaServicio Medicina Digestiva, Hospital Universitario de Basurto, Bilbao, Spain.
Rufo LorenteServicio Medicina Digestiva, Hospital General Ciudad Real, Ciudad Real, Spain.
Montserrat RiveroServicio Medicina Digestiva, Hospital Universitario Marqués de Valdecilla and IDIVAL, Santander, Spain.
Eva IglesiasServicio Medicina Digestiva, Hospital Universitario Reina Sofía, Córdoba, Spain.
Belén HerrerosServicio Medicina Digestiva, Hospital Marina Baixa, Villajoyosa, Spain.
David BusquetsServicio Medicina Digestiva, Hospital de Girona Dr. Trueta/ICO, Girona, Spain.
Joan RieraServicio Medicina Digestiva, Hospital Universitario Son LLàtzer, Palma de Mallorca, Spain.
María Pilar Martínez-MontielServicio Medicina Digestiva, Hospital 12 de Octubre, Madrid, Spain.
Marta RoldónServicio Cirugía General y del Aparato Digestivo, Hospital San Jorge, Huesca, Spain.
Oscar RonceroServicio Medicina Digestiva, Hospital General La Mancha Centro, Ciudad Real, Spain.
Esther HinojosaServicio Medicina Digestiva, Hospital de Manises, Valencia, Spain.
Mónica SierraServicio Medicina Digestiva, Complejo Asistencial Universitario de León, León, Spain.
Jesús BarrioHospital Universitario Rio Hortega, Valladolid, Spain.
Ruth De FranciscoHospital Universitario Central de Asturias and ISPA, Oviedo, Spain.
José HuguetConsorcio Hospital General Universitario de Valencia, Valencia, Spain.
Olga MerinoServicio Medicina Digestiva, Hospital de Cruces, Bilbao, Spain.
Daniel CarpioComplejo Hospitalario Universitario Pontevedra, Pontevedra, Spain.
Daniel GinardServicio Medicina Digestiva, Hospital Universitario Son Espases, Palma de Mallorca, Spain.
Fernando MuñozServicio Medicina Digestiva, Hospital Clínico Universitario Salamanca, Salamanca, Spain.
Marta PiquerasServicio Medicina Digestiva, Consorci Sanitari Terrasa, Barcelona, Spain.
Pedro AlmelaServicio Medicina Digestiva, Hospital General Universitario Castellón, Castellón de la Plana, Spain.
Federico Argüelles-AriasServicio Medicina Digestiva, Hospital Universitario Virgen Macarena, Sevilla, Spain.
Guillermo AlcaínServicio Medicina Digestiva, Hospital Clínico Virgen de la Victoria, Málaga, Spain.
Luis BujandaCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
Noemí ManceñidoServicio Medicina Digestiva, Hospital Infanta Sofía, Madrid, Spain.
Alfredo J LucendoCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
Pilar VarelaServicio Medicina Digestiva, Hospital Cabueñes, Gijón, Spain.
Iago Rodríguez-LagoServicio de Aparato Digestivo, Hospital Universitario de Galdakao, IIS Biocruces, Galdakao, Spain.
Laura RamosServicio Medicina Digestiva, Hospital Universitario La Laguna, Santa Cruz Tenerife, Spain.
Laura SempereServicio Medicina Digestiva, Hospital General Universitario Alicante, Alicante, Spain.
Eva SeséServicio Medicina Digestiva, Hospital Arnau de Vilanova, Lleida, Spain.
Manuel Barreiro-de AcostaServicio Aparato Digestivo, Hospital Universitario Santiago, Santiago de Compostela, Spain.
Eugeni DomènechCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
Rubén FrancésIIS Isabial, Hospital General Universitario Alicante, Alicante, Spain.
Hospital General Universitario de Alicante Doctor Balmis · ESInstituto de Salud Carlos III · ESCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas · ESHospital General Universitario de Ciudad Real · ESAlthaia · ESBellvitge University Hospital · ESComplejo Asistencial Universitario de Palencia · ESComplejo Hospitalario de Navarra · ESComplejo Hospitalario de Pontevedra · ESComplejo Hospitalario Universitario de Santiago · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESConsorci Sanitari de Terrassa · ESHospital Arnau de Vilanova · ESHospital Clínico San Carlos · ESHospital Clínico Universitario de Valencia · ESHospital Clínico Universitario de Valladolid · ESHospital Clínico Universitario Lozano Blesa · ESHospital Clínico Universitario Virgen de la Victoria · ESHospital de Basurto · ESHospital de Cruces · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies comparing immigrant ethnic groups and native patients with IBD have yielded clinical and phenotypic differences. To date, no study has focused on the immigrant IBD population in Spain.

methodsProspective, observational, multicenter study comparing cohorts of IBD patients from ENEIDA-registry who were born outside Spain with a cohort of native patients.

resultsWe included 13,524 patients (1,864 immigrant and 11,660 native). The immigrants were younger (45 ± 12 vs. 54 ± 16 years,

conclusionsCompared with native-born patients, first-generation-immigrant IBD patients in Spain were younger at disease onset and showed an increased risk of having extraintestinal manifestations and using biologics. Our study suggests a featured phenotype of immigrant IBD patients in Spain, and constitutes a new landmark in the epidemiological characterization of immigrant IBD populations in Southern Europe.

Indexed as

biologicsCrohn's diseaseimmigrantinflammatory bowel diseasephenotypeulcerative colitis

Identifiers

PMID35178413
PMCPMC8844561
OpenAlexW4210499323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.