Evidence map›Paper›PMID 35178390›Full record

ArticleFrontiers in cell and developmental biology2022

Six1 and Six2 of the Sine Oculis Homeobox Subfamily are Not Functionally Interchangeable in Mouse Nephron Formation.

Jinshu Xu, Jun Li, Aarthi Ramakrishnan, Hanen Yan, Li Shen, Pin-Xian Xu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. SIX3 as a Regulator of Development and Disease.Journal of developmental biology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jinshu XuDepartment of Genetics and Genomic Sciences, New York, NY, United States.
Jun LiDepartment of Genetics and Genomic Sciences, New York, NY, United States.
Aarthi RamakrishnanDepartment of Neurosciences, New York, NY, United States.
Hanen YanDepartment of Genetics and Genomic Sciences, New York, NY, United States.
Li ShenDepartment of Neurosciences, New York, NY, United States.
Pin-Xian XuDepartment of Genetics and Genomic Sciences, New York, NY, United States.
Pediatrics and Genetics · US

Funding

Transcription factors in kidney developmentR01DK064640 · NIDDK · MC LAUGHLIN RESEARCH INSTITUTE · PI PIN-XIAN XU · 2003 to 2026
$8.9M
NIDDK NIH HHS R01 DK064640
6 · The paper itself

Abstract

The vertebrate Six1 and Six2 arose by gene duplication from the

Indexed as

differentiationgene duplicationmaintenancenephron progenitorSix1 and Six2vertebrate evolution

Identifiers

PMID35178390
PMCPMC8844495
OpenAlexW4210547544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.