Evidence map›Paper›PMID 35178379›Full record

ArticleFrontiers in chemistry2021

In Planta Production of the Receptor-Binding Domain From SARS-CoV-2 With Human Blood Group A Glycan Structures.

Julia König-Beihammer, Ulrike Vavra, Yun-Ji Shin, Christiane Veit, Clemens Grünwald-Gruber, Yasmin Gillitschka, Jasmin Huber, Manuela Hofner, Klemens Vierlinger, Dieter Mitteregger and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. EngineeringBiotechnology reports (Amsterdam, Netherlands) · 2025
    Article
  3. Article
  4. Review
  5. Trafficking and localization of Golgi-residentFrontiers in plant science · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Investigation of theMolecules (Basel, Switzerland) · 2022
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Julia König-BeihammerDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
Ulrike VavraDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
Yun-Ji ShinDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
Christiane VeitDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
Clemens Grünwald-GruberCore Facility Mass Spectrometry, University of Natural Resources and Life Sciences Vienna, Muthgasse, Austria.
Yasmin GillitschkaCore Facility Mass Spectrometry, University of Natural Resources and Life Sciences, Vienna, Austria.
Jasmin HuberCore Facility Mass Spectrometry, University of Natural Resources and Life Sciences, Vienna, Austria.
Manuela HofnerCore Facility Mass Spectrometry, University of Natural Resources and Life Sciences, Vienna, Austria.
Klemens VierlingerCore Facility Mass Spectrometry, University of Natural Resources and Life Sciences, Vienna, Austria.
Dieter MittereggerLaboratory Dr. Kosak, Dr. Reckendorfer, Vienna, Austria.
Andreas WeinhäuselCore Facility Mass Spectrometry, University of Natural Resources and Life Sciences, Vienna, Austria.
Richard StrasserDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
BOKU University · AT

Funding

Austrian Science Fund FWF P 31920
6 · The paper itself

Abstract

Glycosylation of viral envelope proteins is important for infectivity and immune evasion. The SARS-CoV-2 spike protein is heavily glycosylated and host-derived glycan modifications contribute to the formation of specific immunogenic epitopes, enhance the virus-cell interaction or affect virus transmission. On recombinant viral antigens used as subunit vaccines or for serological assays, distinct glycan structures may enhance the immunogenicity and are recognized by naturally occurring antibodies in human sera. Here, we performed an

Indexed as

blood group antigencarbohydrateglycoengineeringglycosylationposttranslational modificationvirus

Identifiers

PMID35178379
PMCPMC8846405
OpenAlexW4210710271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.