Evidence map›Paper›PMID 35178273›Full record

ArticleJournal of pediatric intensive care2022

Adenoviral Respiratory Infection-Associated Mortality in Children: A Retrospective Case Series.

Michael C Spaeder, Claire Stewart, Matthew P Sharron, Julia R Noether, Natalia Martinez-Schlurman, Robert P Kavanagh, Jessica K Signoff, Michael C McCrory, Daniel B Eidman, Anjali V Subbaswamy and 5 more

Open access · greenAbstract read
In one paragraph

Article in Journal of pediatric intensive care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Pathobiology, Severity, and Risk Stratification of Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 13 institutions in 1 country.

Michael C SpaederDivision of Pediatric Critical Care, Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia, United States.ORCID 0000-0002-6175-8435
Claire StewartDivision of Critical Care Medicine, Nationwide Children's Hospital, Columbus, Ohio, United States.
Matthew P SharronDivision of Critical Care Medicine, Children's National Hospital, Washington, District of Columbia, United States.
Julia R NoetherDivision of Pediatric Critical Care, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, United States.ORCID 0000-0001-8809-3931
Natalia Martinez-SchlurmanDivision of Pediatric Critical Care, University of Florida School of Medicine, Gainesville, Florida, United States.ORCID 0000-0002-6798-7482
Robert P KavanaghDivision of Pediatric Critical Care, Pennsylvania State University School of Medicine, Hershey, Pennsylvania, United States.
Jessica K SignoffDivision of Pediatric Critical Care, University of California at Davis School of Medicine, Sacramento, California, United States.ORCID 0000-0001-7883-816X
Michael C McCroryPediatric Critical Care, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States.
Daniel B EidmanPediatric Critical Care, Yale University School of Medicine, New Haven, Connecticut, United States.ORCID 0000-0001-6179-341X
Anjali V SubbaswamyDivision of Pediatric Critical Care, University of New Mexico School of Medicine, Albuquerque, New Mexico, United States.
Paul L SheaDivision of Pediatric Critical Care, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States.
Ilana Harwayne-GidanskyDivision of Pediatric Critical Care, Renaissance School of Medicine at Stony Brook University, Stony Brook, New York, United States.
Emily K NinmerDivision of Pediatric Critical Care, Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia, United States.
Mary Lynn SheramDepartment of Pediatrics, Medical College of Georgia at Augusta University, Augusta, Georgia, United States.
Christopher M WatsonDepartment of Pediatrics, Medical College of Georgia at Augusta University, Augusta, Georgia, United States.
Augusta University · USUniversity of Virginia · USChildren's National · USJohns Hopkins University · USNationwide Children's Hospital · USPennsylvania State University · USStony Brook School · USUniversity of California, Davis · USUniversity of Florida · USUniversity of New Mexico · USUniversity of North Carolina at Chapel Hill · USWake Forest University · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral respiratory infections are a leading cause of illness and hospitalization in young children worldwide. Case fatality rates in pediatric patients with adenoviral lower respiratory tract infection requiring intensive care unit (ICU) admission have been reported between 7 and 22%. We investigated the demographics and clinical characteristics in pediatric mortalities associated with adenoviral respiratory infection at 12 academic children's hospitals in the United States. There were 107 mortality cases included in our study, 73% of which had a chronic medical condition. The most common chronic medical condition was immunocompromised state in 37 cases (35%). The incidences of pediatric acute respiratory distress syndrome (78%) and multiple organ dysfunction syndrome (94%) were profound. Immunocompetent cases were more likely to receive mechanical ventilation within the first hour of ICU admission (60 vs. 14%,

Indexed as

adenoviruschildrenintensive carepediatricrespiratory tract infections

Identifiers

PMID35178273
PMCPMC8843406
OpenAlexW3096475494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.