Evidence map›Paper›PMID 35178180›Full record

ArticleACS medicinal chemistry letters2022

Flavonol-Based Carbon Monoxide Delivery Molecule with Endoplasmic Reticulum, Mitochondria, And Lysosome Localization.

Livia S Lazarus, C Taylor Dederich, Stephen N Anderson, Abby D Benninghoff, Lisa M Berreau

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Iron Porphyrin-mediated Production of Carbon Monoxide from Phenylpyruvic Acid: From Potential Therapeutic and Diagnostic Use to Physiological Implications.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2024
    Article
  4. Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Livia S LazarusDepartment of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300, United States.ORCID https://orcid.org/0000-0002-3001-3190
C Taylor DederichDepartment of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300, United States.ORCID https://orcid.org/0000-0002-8245-7914
Stephen N AndersonDepartment of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300, United States.
Abby D BenninghoffDepartment of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah 84322-4815, United States.ORCID https://orcid.org/0000-0002-7993-0117
Lisa M BerreauDepartment of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300, United States.ORCID https://orcid.org/0000-0001-9599-5239

Funding

Chemical Tools for Delivery of Carbon MonoxideR15GM124596 · NIGMS · UTAH STATE UNIVERSITY · PI BERREAU, LISA M · 2017 to 2023
$861k
NIGMS NIH HHS R15 GM124596
6 · The paper itself

Abstract

Light-triggered carbon monoxide (CO) delivery molecules are of significant current interest for evaluating the role of CO in biology and as potential therapeutics. Herein we report the first example of a metal free CO delivery molecule that can be tracked via confocal microscopy at low micromolar concentrations in cells prior to CO release. The NEt

Identifiers

PMID35178180
PMCPMC8842101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.