Evidence map›Paper›PMID 35178171›Full record

ArticleACS medicinal chemistry letters2022

Synthesis and Metabolism of BTN3A1 Ligands: Studies on Diene Modifications to the Phosphoantigen Scaffold.

Nyema M Harmon, Michael M Poe, Xueting Huang, Rohit Singh, Benjamin J Foust, Chia-Hung Christine Hsiao, David F Wiemer, Andrew J Wiemer

Open access · greenAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Efficiency of bis-amidate phosphonate prodrugs.Bioorganic & medicinal chemistry letters · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nyema M HarmonDepartment of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.ORCID https://orcid.org/0000-0001-9996-0332
Michael M PoeDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092, United States.
Xueting HuangDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092, United States.
Rohit SinghDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092, United States.
Benjamin J FoustDepartment of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.
Chia-Hung Christine HsiaoDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092, United States.ORCID https://orcid.org/0000-0002-9037-027X
David F WiemerDepartment of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.ORCID https://orcid.org/0000-0002-4881-8544
Andrew J WiemerDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092, United States.ORCID https://orcid.org/0000-0002-3029-1780
University of Connecticut · USUniversity of Iowa · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Role of immune modulating butyrophilins in gamma delta T cell activationR01AI150869 · NIAID · UNIVERSITY OF CONNECTICUT STORRS · PI VINOGRADOVA, OLGA, WIEMER, ANDREW J · 2020 to 2024
$2.0M
NIAID NIH HHS R01 AI150869
6 · The paper itself

Abstract

Phosphoantigens (pAgs) are small organophosphorus compounds such as (

Identifiers

PMID35178171
PMCPMC8842111
OpenAlexW4210391257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.