ArticleJournal of oncology2022
Clinical Efficacy and Adverse Reactions of Bevacizumab plus Radiochemotherapy in the Treatment of Advanced Gastric Cancer.
Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
- Efficacy and safety of neoadjuvant bevacizumab plus chemotherapy in locally advanced gastric cancer patients: a retrospective, comparative study.World journal of surgical oncology · 2025Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the clinical efficacy and adverse reactions of bevacizumab plus radiochemotherapy in the treatment of advanced gastric cancer.
methodsEighty-six eligible patients with gastric cancer treated in our institution from August 2019 to August 2020 were recruited and concurrently randomly assigned via the random number table method at a 1 : 1 ratio to receive neoadjuvant radiochemotherapy (control group) or bevacizumab (given on the first day of each course of neoadjuvant radiochemotherapy) plus neoadjuvant radiochemotherapy (study group) for 9 weeks (3 weeks as one course). Outcomes include the clinical efficacy and serum tumor marker levels before and after treatment. Patients in both groups were followed up for 12 months after treatment to obtain progression-free survival (PFS). Assessment of patients' quality of survival was done by the Karnofsky performance score (KPS). The occurrence of adverse reactions in patients during treatment was monitored to evaluate the safety of the treatment protocol.
resultsThe research group outperformed the control group significantly in terms of total treatment efficiency (
conclusionBevacizumab potentiates the treatment outcomes for advanced gastric cancer by effectively attenuating the abnormalities of serum tumor marker levels and prolonging survival, with a high safety profile, in combination with radiochemotherapy versus radiochemotherapy alone.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.