Evidence map›Paper›PMID 35178029›Full record

ArticleFrontiers in endocrinology2021

Luteolin Potentially Treating Prostate Cancer and COVID-19 Analyzed by the Bioinformatics Approach: Clinical Findings and Drug Targets.

Yu Ye, Ziyan Huang, Manying Chen, Yongfeng Mo, Zengnan Mo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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  6. Application of Luteolin in Neoplasms and Nonneoplastic Diseases.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yu YeDepartment of Urology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Ziyan HuangHealth Management Department, First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Manying ChenCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, China.
Yongfeng MoCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, China.
Zengnan MoDepartment of Urology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Guangxi Medical University · CNFirst Affiliated Hospital of GuangXi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is a serious epidemic, characterized by potential mutation and can bring about poor vaccine efficiency. It is evidenced that patients with malignancies, including prostate cancer (PC), may be highly vulnerable to the SARS-CoV-2 infection. Currently, there are no existing drugs that can cure PC and COVID-19. Luteolin can potentially be employed for COVID-19 treatment and serve as a potent anticancer agent. Our present study was conducted to discover the possible drug target and curative mechanism of luteolin to serve as treatment for PC and COVID-19. The differential gene expression of PC cases was determined

Indexed as

COVID-19 Drug TreatmentComputational BiologyCOVID-19Drug DiscoveryHigh-Throughput Screening AssaysHumansLuteolinMaleMetabolic Networks and PathwaysModels, MolecularMolecular Docking SimulationMolecular Targeted TherapyProstatic NeoplasmsProtein Interaction MapsSARS-CoV-2Luteolinclinical featureCOVID-19drug targetluteolinmechanismprostate cancer

Identifiers

PMID35178029
PMCPMC8844187
OpenAlexW4210519192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.